Microorganism genomics, compositions and methods related thereto

Handelsman, Jo; Goodman, Robert M; Rondon, Michelle R

Title: Microorganism genomics, compositions and methods related thereto

Patent · Mon Jan 01 00:00:00 EST 2001

OSTI ID:873859

Handelsman, Jo ^[1]; Goodman, Robert M ^[1]; Rondon, Michelle R ^[1]

Madison, WI

The present invention provides methods and compositions for accessing, in a generally unbaised manner, a diverse genetic pool for genes involved in biosynthetic pathways. The invention also provides compounds which can be identified by cloning biosynthetic pathways.

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Research Organization:: Univ. of Wisconsin, Madison, WI (United States)

DOE Contract Number:: FG02-96ER20248

Assignee:: Wisconsin Alumni Research Foundation (Madison, WI)

Patent Number(s):: US 6261842

OSTI ID:: 873859

Country of Publication:: United States

Language:: English

References (11)

Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome Messerle, M.; Crnkovic, I.; Hammerschmidt, W. Proceedings of the National Academy of Sciences, Vol. 94, Issue 26 https://doi.org/10.1073/pnas.94.26.14759	journal	December 1997
Molecular phylogeny of Archaea from soil Bintrim, S. B.; Donohue, T. J.; Handelsman, J. Proceedings of the National Academy of Sciences, Vol. 94, Issue 1 https://doi.org/10.1073/pnas.94.1.277	journal	January 1997
Use of a Mycobacterium tuberculosisH37Rv Bacterial Artificial Chromosome Library for Genome Mapping, Sequencing, and Comparative Genomics Brosch, Roland; Gordon, Stephen V.; Billault, Alain Infection and Immunity, Vol. 66, Issue 5 https://doi.org/10.1128/IAI.66.5.2221-2229.1998	journal	May 1998
A new bacteriophage P1–derived vector for the propagation of large human DNA fragments loannou, Panayiotis A.; Amemiya, Chris T.; Garnes, Jeffrey Nature Genetics, Vol. 6, Issue 1 https://doi.org/10.1038/ng0194-84	journal	January 1994
Construction and characterization of bacterial artificial chromosome library of Sorghum bicolor Woo, Sung-Sick; Jiang, Jiming; Gill, Bikram S. Nucleic Acids Research, Vol. 22, Issue 23 https://doi.org/10.1093/nar/22.23.4922	journal	January 1994
dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues Ohmori, Haruo; Hatada, Eriko; Qiao, Ying Mutation Research Letters, Vol. 347, Issue 1 https://doi.org/10.1016/0165-7992(95)90024-1	journal	June 1995
Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. Woese, C. R.; Kandler, O.; Wheelis, M. L. Proceedings of the National Academy of Sciences, Vol. 87, Issue 12 https://doi.org/10.1073/pnas.87.12.4576	journal	June 1990
Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. Shizuya, H.; Birren, B.; Kim, U. J. Proceedings of the National Academy of Sciences, Vol. 89, Issue 18 https://doi.org/10.1073/pnas.89.18.8794	journal	September 1992
YACs, BACs, PACs and MACs: Artificial chromosomes as research tools Monaco, Anthony P.; Larin, Zoia Trends in Biotechnology, Vol. 12, Issue 7 https://doi.org/10.1016/0167-7799(94)90140-6	journal	July 1994
Construction and Characterization of a Human Bacterial Artificial Chromosome Library Kim, Ung-Jin; Birren, Bruce W.; Slepak, Tatiana Genomics, Vol. 34, Issue 2 https://doi.org/10.1006/geno.1996.0268	journal	June 1996
Archaeal ubiquity. Stein, J. L.; Simon, M. I. Proceedings of the National Academy of Sciences, Vol. 93, Issue 13 https://doi.org/10.1073/pnas.93.13.6228	journal	June 1996

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Related Subjects

microorganism
genomics
compositions
methods
related
provides
accessing
unbaised
manner
diverse
genetic
pool
genes
involved
biosynthetic
pathways
compounds
identified
cloning
provides methods
methods related
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Title: Microorganism genomics, compositions and methods related thereto

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References (11)

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