Boron-containing amino carboxylic acid compounds and uses thereof
Abstract
Novel compounds which are useful for boron neutron capture therapy (BNCT) are disclosed. The compounds comprise a stable boron-containing group and an aminocycloalkane carboxylic acid group or a boronated acyclic hydrocarbon-linked amino carboxylic acid. Methods for synthesis of the compounds and for use of the compounds in BNCT are disclosed.
- Inventors:
-
- Knoxville, TN
- Publication Date:
- Research Org.:
- Univ. of Tennessee, Knoxville, TN (United States)
- OSTI Identifier:
- 872909
- Patent Number(s):
- US 6037490
- Application Number:
- 08/923,054
- Assignee:
- University of Tennessee Research Corporation (Knoxville, TN)
- DOE Contract Number:
- FG05-93ER61610
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- boron-containing; amino; carboxylic; acid; compounds; novel; useful; boron; neutron; capture; therapy; bnct; disclosed; comprise; stable; aminocycloalkane; boronated; acyclic; hydrocarbon-linked; methods; synthesis; neutron capture; boron neutron; carboxylic acid; capture therapy; novel compounds; acid compounds; acid compound; containing amino; compounds comprise; novel compound; /999/
Citation Formats
Kabalka, George W, and Srivastava, Rajiv R. Boron-containing amino carboxylic acid compounds and uses thereof. United States: N. p., 2000.
Web.
Kabalka, George W, & Srivastava, Rajiv R. Boron-containing amino carboxylic acid compounds and uses thereof. United States.
Kabalka, George W, and Srivastava, Rajiv R. 2000.
"Boron-containing amino carboxylic acid compounds and uses thereof". United States. https://www.osti.gov/servlets/purl/872909.
@article{osti_872909,
title = {Boron-containing amino carboxylic acid compounds and uses thereof},
author = {Kabalka, George W and Srivastava, Rajiv R},
abstractNote = {Novel compounds which are useful for boron neutron capture therapy (BNCT) are disclosed. The compounds comprise a stable boron-containing group and an aminocycloalkane carboxylic acid group or a boronated acyclic hydrocarbon-linked amino carboxylic acid. Methods for synthesis of the compounds and for use of the compounds in BNCT are disclosed.},
doi = {},
url = {https://www.osti.gov/biblio/872909},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 14 00:00:00 EST 2000},
month = {Tue Mar 14 00:00:00 EST 2000}
}
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