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Title: DNA complexes with dyes designed for energy transfer as fluorescent markers

Abstract

Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.

Inventors:
 [1];  [2]
  1. Orinda, CA
  2. Albany, CA
Publication Date:
Research Org.:
Univ. of California (United States)
OSTI Identifier:
872630
Patent Number(s):
US 5977344
Assignee:
Regents of University of California (Berkeley, CA)
DOE Contract Number:  
FG03-91ER61125
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
dna; complexes; dyes; designed; energy; transfer; fluorescent; markers; heteromultimeric; fluorophores; provided; binding; allow; detection; electrical; separations; preparation; probes; high-fluorescent; efficiencies; stokes; shifts; addition; appropriate; choice; molecules; single; narrow; wavelength; band; excitation; light; source; obtaining; emissions; sufficient; separation; readily; discriminated; stokes shifts; dyes designed; fluorescent molecules; single narrow; energy transfer; light source; excitation light; fluorescent emissions; wavelength band; narrow wavelength; readily discriminated; obtaining fluorescent; sufficient separation; electrical separations; dna complexes; high-fluorescent efficiencies; heteromultimeric fluorophores; fluorescent markers; band excitation; appropriate choice; fluorescent emission; stokes shift; /999/

Citation Formats

Glazer, Alexander M, and Benson, Scott C. DNA complexes with dyes designed for energy transfer as fluorescent markers. United States: N. p., 1999. Web.
Glazer, Alexander M, & Benson, Scott C. DNA complexes with dyes designed for energy transfer as fluorescent markers. United States.
Glazer, Alexander M, and Benson, Scott C. Fri . "DNA complexes with dyes designed for energy transfer as fluorescent markers". United States. https://www.osti.gov/servlets/purl/872630.
@article{osti_872630,
title = {DNA complexes with dyes designed for energy transfer as fluorescent markers},
author = {Glazer, Alexander M and Benson, Scott C},
abstractNote = {Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

Patent:

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