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Title: Fiber optic D dimer biosensor

Abstract

A fiber optic sensor for D dimer (a fibrinolytic product) can be used in vivo (e.g., in catheter-based procedures) for the diagnosis and treatment of stroke-related conditions in humans. Stroke is the third leading cause of death in the United States. It has been estimated that strokes and stroke-related disorders cost Americans between $15-30 billion annually. Relatively recently, new medical procedures have been developed for the treatment of stroke. These endovascular procedures rely upon the use of microcatheters. These procedures could be facilitated with this sensor for D dimer integrated with a microcatheter for the diagnosis of clot type, and as an indicator of the effectiveness, or end-point of thrombolytic therapy.

Inventors:
 [1];  [2]
  1. (Livermore, CA)
  2. (Pleasanton, CA)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
872449
Patent Number(s):
US 5938595
Assignee:
Regents of University of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
fiber; optic; dimer; biosensor; sensor; fibrinolytic; product; vivo; catheter-based; procedures; diagnosis; treatment; stroke-related; conditions; humans; stroke; third; leading; death; united; estimated; strokes; disorders; cost; americans; $15-30; billion; annually; relatively; recently; medical; developed; endovascular; rely; microcatheters; facilitated; integrated; microcatheter; clot; type; indicator; effectiveness; end-point; thrombolytic; therapy; medical procedures; fiber optic; optic sensor; stroke-related conditions; /600/356/

Citation Formats

Glass, Robert S., and Grant, Sheila A. Fiber optic D dimer biosensor. United States: N. p., 1999. Web.
Glass, Robert S., & Grant, Sheila A. Fiber optic D dimer biosensor. United States.
Glass, Robert S., and Grant, Sheila A. Fri . "Fiber optic D dimer biosensor". United States. doi:. https://www.osti.gov/servlets/purl/872449.
@article{osti_872449,
title = {Fiber optic D dimer biosensor},
author = {Glass, Robert S. and Grant, Sheila A.},
abstractNote = {A fiber optic sensor for D dimer (a fibrinolytic product) can be used in vivo (e.g., in catheter-based procedures) for the diagnosis and treatment of stroke-related conditions in humans. Stroke is the third leading cause of death in the United States. It has been estimated that strokes and stroke-related disorders cost Americans between $15-30 billion annually. Relatively recently, new medical procedures have been developed for the treatment of stroke. These endovascular procedures rely upon the use of microcatheters. These procedures could be facilitated with this sensor for D dimer integrated with a microcatheter for the diagnosis of clot type, and as an indicator of the effectiveness, or end-point of thrombolytic therapy.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1999},
month = {Fri Jan 01 00:00:00 EST 1999}
}

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