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Real time chemical exposure and risk monitor

Patent ·
OSTI ID:871033
 [1];  [2];  [3];  [4]
  1. 3804 Alder Lake Ct., West Richland, WA 99353
  2. 6947 Sparrow La., Worthington, OH 43235
  3. 2112 Briarwood Ct., Richland, WA 99352
  4. 1211 Marshall Ave., Richland, WA 99352
+ Show Author Affiliations

The apparatus of the present invention is a combination of a breath interface and an external exposure dosimeter interface to a chemical analysis device, all controlled by an electronic processor for quantitatively analyzing chemical analysis data from both the breath interface and the external exposure dosimeter for determining internal tissue dose. The method of the present invention is a combination of steps of measuring an external dose, measuring breath content, then analyzing the external dose and breath content and determining internal tissue dose.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA
DOE Contract Number:
AC06-76RL01830
Assignee:
Thrall, Karla D. (3804 Alder Lake Ct., West Richland, WA 99353);Kenny, Donald V. (6947 Sparrow La., Worthington, OH 43235);Endres, George W. R. (2112 Briarwood Ct., Richland, WA 99352);Sisk, Daniel R. (1211 Marshall Ave., Richland, WA 99352)
Patent Number(s):
US 5645072
OSTI ID:
871033
Country of Publication:
United States
Language:
English

References (9)

A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans journal March 1984
The use of triple quadrupoles for sequential mass spectrometry: 1—The instrument parameters journal May 1982
A Device for Sampling of Human Alveolar Breath for the Measurement of Expired Volatile Organic Compounds journal November 1990
Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathways journal February 1986
The use of triple quadrupoles for sequential mass spectrometry: 2—A detailed case study journal May 1982
A physiologically based pharmacokinetic model for inhaled carbon tetrachloride journal November 1988
A physiologically based simulation approach for determining metabolic constants from gas uptake data journal December 1986
A Canister-Based Method for Collection and GC/MS Analysis of Volatile Organic Compounds in Human Breath journal March 1991
Assessment of Exposure to Pulmonary Toxicants: Use of Biological Markers journal January 1992

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Related Subjects

/600/
analysis
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electronic
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interface
internal
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