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Recombinant HT.sub.m4 gene, protein and assays

Patent ·
OSTI ID:870590
 [1];  [2];  [3]
  1. Dorcester, MA
  2. Boston, MA
  3. Toulouse, FR
+ Show Author Affiliations
The invention relates to a recombinant DNA molecule which encodes a HT.sub.m4 protein, a transformed host cell which has been stably transfected with a DNA molecule which encodes a HT.sub.m4 protein and a recombinant HT.sub.m4 protein. The invention also relates to a method for detecting the presence of a hereditary atopy.
Research Organization:
University of Chicago
DOE Contract Number:
FG02-86ER60408
Assignee:
Beth Israel Hospital Boston (Boston, MA)
Patent Number(s):
US 5552312
OSTI ID:
870590
Country of Publication:
United States
Language:
English

References (12)

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions. journal October 1994
A major gene for allergy — fact or fancy? journal December 1992
Atopy and Fc receptors: mutation is the message? journal June 1994
The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor. journal June 1992
Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E. journal September 1988
Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells journal September 1989
Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor journal June 1994
Maternal inheritance of atopic IgE responsiveness on chromosome 11 q journal August 1992
Determination of the sequence coding for the β subunit of the human high-affinity IgE receptor journal May 1992
Allergy by mutation journal June 1994
LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q journal June 1989
Fc Receptors journal April 1991

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assays
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hereditary atopy
host
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m4
m4 protein
method
molecule
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recombinant
recombinant dna
relates
stably
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