Methods for chromosome-specific staining

Gray, Joe W; Pinkel, Daniel

Title: Methods for chromosome-specific staining

Patent · Sun Jan 01 00:00:00 EST 1995

OSTI ID:870054

Gray, Joe W ^[1]; Pinkel, Daniel ^[2]

Livermore, CA
Walnut Creek, CA

Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

DOE Contract Number:: W-7405-ENG-48

Assignee:: Regents Of Univ. Of California (Oakland, CA)

Patent Number(s):: US 5447841

OSTI ID:: 870054

Country of Publication:: United States

Language:: English

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methods
chromosome-specific
staining
compositions
provided
comprise
heterogenous
mixtures
labeled
nucleic
acid
fragments
substantially
complementary
base
sequences
unique
sequence
regions
chromosomal
dna
associated
reagent
specific
applying
chromosomes
compositions comprise
base sequences
chromosomal dna
nucleic acid
base sequence
chromosome-specific staining
complementary base
substantially complementary
staining reagent
acid fragment
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Title: Methods for chromosome-specific staining

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References (68)

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