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Title: Process for the separation and purification of yttrium-90 for medical applications

Patent ·
OSTI ID:869624

An extraction chromatographic method for the preparation of .sup.90 Y of high chemical and radiochemical purity is disclosed. After an initial purification of a .sup.90 Sr stock solution and a suitable period of .sup.90 Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the .sup.90 Sr content of the mixture by a factor of about 10.sup.3. The .sup.90 Y remaining is freed from any residual .sup.90 Sr, from its .sup.90 Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
DOE Contract Number:
W-31109-ENG-38
Assignee:
United States of America as represented by United States (Washington, DC)
Patent Number(s):
US 5368736
OSTI ID:
869624
Country of Publication:
United States
Language:
English

References (3)

The preparation of a rubidium-82 radionuclide generator journal March 1981
Chemistry for commercial scale production of yttrium-90 for medical research journal January 1990
Improved chemistry for the production of yttrium-90 for medical applications journal September 1992