Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid

Patent · 31 December 1991

OSTI ID:868159

Atcher, Robert W ^[1]; Hines, John J ^[2]

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1. Chicago, IL
2. Glen Ellyn, IL

A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

• Research Organization: Argonne National Laboratory (ANL), Argonne, IL
• DOE Contract Number: W-31109-ENG-38
• Assignee: United States of America as Represented by United States (Washington, DC)
• Patent Number(s): US 5085848
• OSTI ID: 868159
• Country of Publication: United States
• Language: English

Related Subjects

/424/252/600/
alpha-emitting
alpha-emitting radionuclide
calloid
cancer
cancer therapy
colloid
diseases
emitting radionuclide
essentially
ferric
ferric hydroxide
ferrous
ferrous hydroxide
form
forming
hydroxide
hydroxide colloid
inflamed
inflamed joints
inflammatory
joints
labelled
labelled colloid
method
outer
outer surface
outer surfaces
oxidizing
preselected
preselected radionuclide
presence
radiolabeled
radionuclide
radionuclide essentially
solution
suitable
suitable solution
surface
surfaces
suspending
therapy
thereafter
thereafter washing
treating
treatment
useful
washed
washed colloid
washing