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Title: Excimer laser phototherapy for the dissolution of abnormal growth

Abstract

Removal of abnormal human tissue with reduced thermal damage is achieved by selecting a laser having a wavelength in the order of 290-400 nm, orienting a laser-transmitting glass member toward the abnormal tissue and directing the laser through the glass member at power densities, pulse rates, and times sufficient to cause multiphoton absorption and bond breaking by Coulomb repulsion rather than thermal destruction. The glass member may include a laser beam concentrator provided by a lens or cone at the tissue-treatment end to increase the beam energy per unit area and reduce the treatment area.

Inventors:
 [1];  [2];  [3]
  1. (Downers Grove, IL)
  2. (Westmont, IL)
  3. (Naperville, IL)
Publication Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL
OSTI Identifier:
866333
Patent Number(s):
US 4686979
Assignee:
United States of America as represented by United States (Washington, DC) ANL
DOE Contract Number:  
W-31109-ENG-38
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
excimer; laser; phototherapy; dissolution; abnormal; growth; removal; human; tissue; reduced; thermal; damage; achieved; selecting; wavelength; 290-400; nm; orienting; laser-transmitting; glass; directing; power; densities; pulse; rates; times; sufficient; multiphoton; absorption; bond; breaking; coulomb; repulsion; destruction; beam; concentrator; provided; lens; cone; tissue-treatment; increase; energy; unit; reduce; treatment; photon absorption; power densities; reduced thermal; thermal damage; laser beam; beam energy; excimer laser; pulse rate; normal human; human tissue; normal tissue; coulomb repulsion; thermal destruction; /606/

Citation Formats

Gruen, Dieter M., Young, Charles E., and Pellin, Michael J.. Excimer laser phototherapy for the dissolution of abnormal growth. United States: N. p., 1987. Web.
Gruen, Dieter M., Young, Charles E., & Pellin, Michael J.. Excimer laser phototherapy for the dissolution of abnormal growth. United States.
Gruen, Dieter M., Young, Charles E., and Pellin, Michael J.. Thu . "Excimer laser phototherapy for the dissolution of abnormal growth". United States. https://www.osti.gov/servlets/purl/866333.
@article{osti_866333,
title = {Excimer laser phototherapy for the dissolution of abnormal growth},
author = {Gruen, Dieter M. and Young, Charles E. and Pellin, Michael J.},
abstractNote = {Removal of abnormal human tissue with reduced thermal damage is achieved by selecting a laser having a wavelength in the order of 290-400 nm, orienting a laser-transmitting glass member toward the abnormal tissue and directing the laser through the glass member at power densities, pulse rates, and times sufficient to cause multiphoton absorption and bond breaking by Coulomb repulsion rather than thermal destruction. The glass member may include a laser beam concentrator provided by a lens or cone at the tissue-treatment end to increase the beam energy per unit area and reduce the treatment area.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1987},
month = {Thu Jan 01 00:00:00 EST 1987}
}

Patent:

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