Antihypertensive neutral lipid

Patent · Wed Jan 01 00:00:00 EST 1986

OSTI ID:865882

Snyder, Fred L ^[1]; Blank, Merle L ^[1]

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1. Oak Ridge, TN

The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.

• Research Organization: Oak Ridge Associated Universities (ORAU), Oak Ridge, TN (United States)
• DOE Contract Number: AC05-76OR00033
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 4595681
• OSTI ID: 865882
• Country of Publication: United States
• Language: English

Related Subjects

antihypertensive
neutral
lipid
relates
discovery
acetylated
ether-linked
glycerolipids
capacity
blood
pressure
warm-blooded
animals
physiological
effect
structure
sensitive
requiring
chain
alkyl
sn-1
position
carbon
acyl
acetyl
propionyl
sn-2
hydroxyl
sn-3
chain alkyl
warm-blooded animals
carbon chain
blood pressure
/514/999/