Generator for gallium-68 and compositions obtained therefrom

Patent · 01 January 1981

OSTI ID:863870

Neirinckx, Rudi D ^[1]; Davis, Michael A ^[2]

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1. Medfield, MA
2. Westwood, MA

A generator for obtaining radioactive gallium-68 from germanium-68 bound in a resin containing unsubstituted phenolic hydroxyl groups. The germanium-68 is loaded into the resin from an aqueous solution of the germanium-68. A physiologically acceptable solution of gallium-68 having an activity of 0.1 to 50 millicuries per milliliter of gallium-68 solution is obtained. The solution is obtained from the bound germanium-68 which forms gallium-68 in situ by eluting the column with a hydrochloric acid solution to form an acidic solution of gallium-68. The acidic solution of gallium-68 can be neutralized.

• Assignee: Massachusetts Institute of Technology (Cambridge, MA)
• Patent Number(s): US 4264468
• OSTI ID: 863870
• Country of Publication: United States
• Language: English

Related Subjects

/424/250/376/422/423/976/
50
acceptable
acceptable solution
acid
acid solution
acidic
acidic solution
activity
aqueous
aqueous solution
bound
column
compositions
containing
eluting
form
forms
gallium-68
generator
germanium-68
hydrochloric
hydrochloric acid
hydroxyl
loaded
millicuries
milliliter
neutralized
obtained
obtaining
phenolic
phenolic hydroxyl
physiologically
physiologically acceptable
radioactive
resin
resin containing
situ
solution
therefrom
unsubstituted