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Title: Final Technical Report on "Metabolic Engineering for Heavy Metal and Actinide Removal�?????�????�???�??�?�¢??

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Univ. of California, Berkeley, CA (United States)
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Resource Type:
Technical Report
Country of Publication:
United States

Citation Formats

Jay D. Keasling. Final Technical Report on "Metabolic Engineering for Heavy Metal and Actinide Removal�?????�????�???�??�?�¢??. United States: N. p., 2005. Web.
Jay D. Keasling. Final Technical Report on "Metabolic Engineering for Heavy Metal and Actinide Removal�?????�????�???�??�?�¢??. United States.
Jay D. Keasling. Mon . "Final Technical Report on "Metabolic Engineering for Heavy Metal and Actinide Removal�?????�????�???�??�?�¢??". United States. doi:.
title = {Final Technical Report on "Metabolic Engineering for Heavy Metal and Actinide Removal�?????�????�???�??�?�¢??},
author = {Jay D. Keasling},
abstractNote = {},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Nov 21 00:00:00 EST 2005},
month = {Mon Nov 21 00:00:00 EST 2005}

Technical Report:

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  • Magnetic adsorbents can be applied to the treatment of waste water in various physical forms. For example, barium ferrite (BaO{center_dot}Fe{sub 2}O{sub 3}) has been used successfully as powder, granules or pellets. Iron ferrite, or magnetite, a naturally occurring ore, can also be used in much the same manner. However, natural magnetic needs activation to have the same capacity as freshly prepared ferrite. Furthermore, ferrites have been used solely in a batch mode because of their finely divided nature. To permit utilization of activated magnetite in a column mode with good water flow-through properties, magnetic resins were prepared. In this work,more » the authors discovered a synergistic effect in using the magnetic resin in a column mode in conjunction with an external magnetic field for concentration of plutonium and americium from waste water. Thus ferrities in a column made surrounded by a magnetic field greatly surpasses the metal removal capacity of ferrite used in a batch mode.« less
  • Welcome to the 2006 joint meeting of the fourth Genomics:GTL Contractor-Grantee Workshop and the six Metabolic Engineering Working Group Inter-Agency Conference. The vision and scope of the Genomics:GTL program continue to expand and encompass research and technology issues from diverse scientific disciplines, attracting broad interest and support from researchers at universities, DOE national laboratories, and industry. Metabolic engineering's vision is the targeted and purposeful alteration of metabolic pathways to improve the understanding and use of cellular pathways for chemical transformation, energy transduction, and supramolecular assembly. These two programs have much complementarity in both vision and technological approaches, as reflected inmore » this joint workshop. GLT's challenge to the scientific community remains the further development and use of a broad array of innovative technologies and computational tools to systematically leverage the knowledge and capabilities brought to us by DNA sequencing projects. The goal is to seek a broad and predictive understanding of the functioning and control of complex systems--individual microbes, microbial communities, and plants. GTL's prominent position at the interface of the physical, computational, and biological sciences is both a strength and challenge. Microbes remain GTL's principal biological focus. In the complex 'simplicity' of microbes, they find capabilities needed by DOE and the nation for clean and secure energy, cleanup of environmental contamination, and sequestration of atmospheric carbon dioxide that contributes to global warming. An ongoing challenge for the entire GTL community is to demonstrate that the fundamental science conducted in each of your research projects brings us a step closer to biology-based solutions for these important national energy and environmental needs.« less
  • This engineering study has been prepared to identify and assess the nature of the impact on the NWRB design, operations plan, schedule, and cost of receiving waste equivalent to 72,000 metric tons of heavy metal (MTHN); which is an increase of 24,600 MTHM over the baseline NWRB design. 4 refs., 9 figs., 41 tabs.
  • Rising energy demands and the imperative to reduce carbon dioxide (CO 2) emissions are driving research on biofuels development. Hydrogen gas (H 2) is one of the most promising biofuels and is seen as a future energy carrier by virtue of the fact that 1) it is renewable, 2) does not evolve the “greenhouse gas” CO 2 in combustion, 3) liberates large amounts of energy per unit weight in combustion (having about 3 times the energy content of gasoline), and 4) is easily converted to electricity by fuel cells. Among the various bioenergy strategies, environmental groups and others say thatmore » the concept of the direct manufacture of alternative fuels, such as H 2, by photosynthetic organisms is the only biofuel alternative without significant negative criticism [1]. Biological H 2 production by photosynthetic microorganisms requires the use of a simple solar reactor such as a transparent closed box, with low energy requirements, and is considered as an attractive system to develop as a biocatalyst for H 2 production [2]. Various purple bacteria including Rhodopseudomonas palustris, can utilize organic substrates as electron donors to produce H 2 at the expense of solar energy. Because of the elimination of energy cost used for H 2O oxidation and the prevention of the production of O 2 that inhibits the H 2-producing enzymes, the efficiency of light energy conversion to H 2 by anoxygenic photosynthetic bacteria is in principle much higher than that by green algae or cyanobacteria, and is regarded as one of the most promising cultures for biological H 2 production [3]. Here implemented a simple and relatively straightforward strategy for hydrogen production by photosynthetic microorganisms using sunlight, sulfur- or iron-based inorganic substrates, and CO 2 as the feedstock. Carefully selected microorganisms with bioengineered beneficial traits act as the biocatalysts of the process designed to both enhance the system efficiency of CO 2 fixation and the net hydrogen production rate. Additionally we applied metabolic engineering approaches guided by computational modeling for the chosen model microorganisms to enable efficient hydrogen production.« less