Adaptive response against spontaneous neoplastic transformation induced by low dose ionizing radiation
This project is being conducted to ascertain the shape of the dose response curve for neoplastic transformation in vitro over the dose range 0.0 to 10 cGy, and how this depends on radiation quality and dose fractionation. Preliminary data already have indicated that at a dose of 1 cGy the induced transformation frequency is less than the spontaneous transformation frequency. The results will be compared with animal and human epidemiological data on the induction of cancer by low doses of radiation. This will hopefully allow for a more informed estimation of the risk of cancer induction at low doses (see Pollycove, 1998; Rossi, 1999).
- Research Organization:
- University of California Irvine (US)
- Sponsoring Organization:
- USDOE Office of Environmental Management (EM) (US)
- DOE Contract Number:
- FG07-99ER62876
- OSTI ID:
- 833309
- Report Number(s):
- EMSP-69848-2000; R&D Project: EMSP 69848; TRN: US200430%%1417
- Resource Relation:
- Other Information: PBD: 1 Jun 2000
- Country of Publication:
- United States
- Language:
- English
Similar Records
Adaptive response against spontaneous neoplastic transformation induced by low dose ionizing radiation
Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation
Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation
Technical Report
·
Fri Jun 01 00:00:00 EDT 2001
·
OSTI ID:833309
Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation
Technical Report
·
Mon Nov 10 00:00:00 EST 2003
·
OSTI ID:833309
Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation
Technical Report
·
Sat Jun 01 00:00:00 EDT 2002
·
OSTI ID:833309