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Title: Genetic Engineering of a Radiation-Resistant Bacterium for Biodegradation of Mixed Wastes

Abstract

The mixture of toxic chemicals, heavy metals, halogenated solvents and radionuclides in many DOE waste materials presents a challenging problem for separating the different species and disposing of individual contaminants. One approach for dealing with mixed wastes is to genetically engineer the radiation-resistant bacterium, Deinococcus radiodurans to survive in and detoxify DOE's mixed waste streams, and to develop process parameters for treating mixed wastes with such constructed strains. The goal for this project is to develop a suite of genetic tools for Deinococcus radiodurans and to use these tools to construct and test stable strains for detoxification of haloorganics in mixed wastes.

Authors:
Publication Date:
Research Org.:
University of Washington, Seattle, WA (US)
Sponsoring Org.:
USDOE Office of Environmental Management (EM) (US)
OSTI Identifier:
828598
Report Number(s):
EMSP-60150-2000
R&D Project: EMSP 60150; TRN: US200427%%524
DOE Contract Number:  
FG07-97ER20294
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: 1 Jun 2000
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 54 ENVIRONMENTAL SCIENCES; BIODEGRADATION; DETOXIFICATION; ENGINEERS; GENETIC ENGINEERING; GENETICS; MIXTURES; RADIOISOTOPES; SOLVENTS; STRAINS; WASTES

Citation Formats

Lidstrom, Mary E. Genetic Engineering of a Radiation-Resistant Bacterium for Biodegradation of Mixed Wastes. United States: N. p., 2000. Web. doi:10.2172/828598.
Lidstrom, Mary E. Genetic Engineering of a Radiation-Resistant Bacterium for Biodegradation of Mixed Wastes. United States. doi:10.2172/828598.
Lidstrom, Mary E. Thu . "Genetic Engineering of a Radiation-Resistant Bacterium for Biodegradation of Mixed Wastes". United States. doi:10.2172/828598. https://www.osti.gov/servlets/purl/828598.
@article{osti_828598,
title = {Genetic Engineering of a Radiation-Resistant Bacterium for Biodegradation of Mixed Wastes},
author = {Lidstrom, Mary E},
abstractNote = {The mixture of toxic chemicals, heavy metals, halogenated solvents and radionuclides in many DOE waste materials presents a challenging problem for separating the different species and disposing of individual contaminants. One approach for dealing with mixed wastes is to genetically engineer the radiation-resistant bacterium, Deinococcus radiodurans to survive in and detoxify DOE's mixed waste streams, and to develop process parameters for treating mixed wastes with such constructed strains. The goal for this project is to develop a suite of genetic tools for Deinococcus radiodurans and to use these tools to construct and test stable strains for detoxification of haloorganics in mixed wastes.},
doi = {10.2172/828598},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {6}
}

Technical Report:

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