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Title: Final Report: Medical University of South Carolina - State Project No. H51-9507-RC - Federal Grant No. DE-FG02-91CH10468

Abstract

The Gazes Cardiac Research Institute became a physical entity in the spring of 1997 as a direct result of a Department of Energy appropriation of 6 million dollars. These monies were contributed with funding from the Medical University of South Carolina and the United States Department of Veterans Affairs to construct a nine story basic research facility to provide a distinct home for the Cardiology Division Research laboratories, VAMC Research laboratories and MUSC and VAMC Animal Facilities. The Gazes Cardiac Research Institute is comprised of one half of the first floor and the entire second floor of this facility. It is dedicated to both basic and clinical investigations of cardiovascular disease with an emphasis on congestive heart failure and myocardial infarction research. Heart failure is the leading cause of death both in South Carolina and in the United States. The Medical University of South Carolina has had a long standing successful research program in cardiovascular disease. The Gazes Cardiac Research Institute was formed in 1987 to provide an institutional and financial commitment at MUSC to adult cardiology research. Dr. George Cooper, IV came to MUSC in 1985 specifically to form a research group comprised of interacting Ph.D. and M.D. scientistmore » to study the phenomenon of cardiac hypertrophic growth. This is study of how the adult heart grows as a result of increased workload placed upon the heart. While initially beneficial, this growth eventually fails to compensate for the increased demands placed upon the heart, and the heart ultimately goes into congestive heart failure. This new facility has benefited our research program in many ways. Previously our laboratories were housed in four separate buildings located as far as 1/2 mile apart from each other. We had molecular biology, protein chemistry, and physiology laboratories located in separate areas because the University did not have adequate space for our program. We now have a basic research facility that is second to none. This state-of-the-art research facility has allowed all of our research operations to relocate into contiguous laboratories. This dramatically increases our efficiency for several reasons. We no longer have to plan how to logistically transfer materials mid-experiment from one location to another. We now have the capability to walk next door to exchange ideas and offer expertise to others. We have widened our areas of research because we now have the physical space to undertake new research endeavors. This has not only furthered our previous research, but has fostered new collaborations as result of frequent interaction amongst our staff. Our old facilities were not constructed for basic research activities and it took a substantial amount of energy to keep them in functioning manner. Now all of our efforts are focused upon the research at hand. We have started new collaborations with intra- and extramural laboratories as a direct result of these new facilities and our increased capacity to perform work. Additionally, our research publications and extramural peer-reviewed funding has increased as a result of this new environment. While not solely linked to our new facilities, these accomplishments would not have occurred without them. We are currently working on hosting an International ,Symposium based on Cellular Physiology for the American Physiology Society for the summer of 2000. One of the primary reasons that we were chosen as a site host, is the paradigm we have built for scholastic interaction and the fine research facilities that we have available here at the Gazes Cardiac Research Institute. In concurrence with our basic research activities, we are now developing community outreach programs to better inform our local community of heart healthy lifestyles and to increase cardiology care awareness. In summary, this Department of Energy appropriations has made a significant and long lasting contribution to improved health care in the state of South Carolina and the nation as a whole.« less

Publication Date:
Research Org.:
Medical University of South Carolina, Gazes Cardiac Research Institute, Charleston, SC (US)
Sponsoring Org.:
US Department of Energy (US)
OSTI Identifier:
804046
DOE Contract Number:  
FG02-91CH10468
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: 8 Jul 2002; PBD: 8 Jul 2002
Country of Publication:
United States
Language:
English
Subject:
29 ENERGY PLANNING, POLICY AND ECONOMY; ANIMALS; CAPACITY; CARDIOVASCULAR DISEASES; CHEMISTRY; EFFICIENCY; HEART FAILURE; MOLECULAR BIOLOGY; MYOCARDIAL INFARCTION; PHYSIOLOGY; PROTEINS; RESEARCH PROGRAMS

Citation Formats

. Final Report: Medical University of South Carolina - State Project No. H51-9507-RC - Federal Grant No. DE-FG02-91CH10468. United States: N. p., 2002. Web. doi:10.2172/804046.
. Final Report: Medical University of South Carolina - State Project No. H51-9507-RC - Federal Grant No. DE-FG02-91CH10468. United States. https://doi.org/10.2172/804046
. 2002. "Final Report: Medical University of South Carolina - State Project No. H51-9507-RC - Federal Grant No. DE-FG02-91CH10468". United States. https://doi.org/10.2172/804046. https://www.osti.gov/servlets/purl/804046.
@article{osti_804046,
title = {Final Report: Medical University of South Carolina - State Project No. H51-9507-RC - Federal Grant No. DE-FG02-91CH10468},
author = {},
abstractNote = {The Gazes Cardiac Research Institute became a physical entity in the spring of 1997 as a direct result of a Department of Energy appropriation of 6 million dollars. These monies were contributed with funding from the Medical University of South Carolina and the United States Department of Veterans Affairs to construct a nine story basic research facility to provide a distinct home for the Cardiology Division Research laboratories, VAMC Research laboratories and MUSC and VAMC Animal Facilities. The Gazes Cardiac Research Institute is comprised of one half of the first floor and the entire second floor of this facility. It is dedicated to both basic and clinical investigations of cardiovascular disease with an emphasis on congestive heart failure and myocardial infarction research. Heart failure is the leading cause of death both in South Carolina and in the United States. The Medical University of South Carolina has had a long standing successful research program in cardiovascular disease. The Gazes Cardiac Research Institute was formed in 1987 to provide an institutional and financial commitment at MUSC to adult cardiology research. Dr. George Cooper, IV came to MUSC in 1985 specifically to form a research group comprised of interacting Ph.D. and M.D. scientist to study the phenomenon of cardiac hypertrophic growth. This is study of how the adult heart grows as a result of increased workload placed upon the heart. While initially beneficial, this growth eventually fails to compensate for the increased demands placed upon the heart, and the heart ultimately goes into congestive heart failure. This new facility has benefited our research program in many ways. Previously our laboratories were housed in four separate buildings located as far as 1/2 mile apart from each other. We had molecular biology, protein chemistry, and physiology laboratories located in separate areas because the University did not have adequate space for our program. We now have a basic research facility that is second to none. This state-of-the-art research facility has allowed all of our research operations to relocate into contiguous laboratories. This dramatically increases our efficiency for several reasons. We no longer have to plan how to logistically transfer materials mid-experiment from one location to another. We now have the capability to walk next door to exchange ideas and offer expertise to others. We have widened our areas of research because we now have the physical space to undertake new research endeavors. This has not only furthered our previous research, but has fostered new collaborations as result of frequent interaction amongst our staff. Our old facilities were not constructed for basic research activities and it took a substantial amount of energy to keep them in functioning manner. Now all of our efforts are focused upon the research at hand. We have started new collaborations with intra- and extramural laboratories as a direct result of these new facilities and our increased capacity to perform work. Additionally, our research publications and extramural peer-reviewed funding has increased as a result of this new environment. While not solely linked to our new facilities, these accomplishments would not have occurred without them. We are currently working on hosting an International ,Symposium based on Cellular Physiology for the American Physiology Society for the summer of 2000. One of the primary reasons that we were chosen as a site host, is the paradigm we have built for scholastic interaction and the fine research facilities that we have available here at the Gazes Cardiac Research Institute. In concurrence with our basic research activities, we are now developing community outreach programs to better inform our local community of heart healthy lifestyles and to increase cardiology care awareness. In summary, this Department of Energy appropriations has made a significant and long lasting contribution to improved health care in the state of South Carolina and the nation as a whole.},
doi = {10.2172/804046},
url = {https://www.osti.gov/biblio/804046}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {7}
}