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Title: Mass Spectrometric Fingerprinting of Tank Waste Using Tunable, Ultrafast Infrared Lasers

Abstract

The principal scientific thrust of this project was to demonstrate a novel method for precision matrix-assisted laser desorption-ionization (MALDI) mass spectrometry (MS) of model tank-waste materials using, using the sodium nitrate component of the tank waste both as the matrix and as an internal calibration standard. Conventional nanosecond and femtosecond single-frequency lasers and a tunable, mid-infrared free-electron laser were used in the development of the MS protocols and in measurements of the MALDI dynamics. In addition to developing a model of the processes which lead to efficient desorption and ionization of organic molecules (e.g., toluene, benzene, chelators, various organic acids, crown ethers) from sodium nitrate, we developed protocols for quantitative analysis based on the use of the sodium nitrate in tank waste as an internal standard. Comparisons of MALDI-MS using nanosecond and picosecond lasers, and of infrared and ultraviolet lasers, have been especially instructive, and demonstrate the superior potential of IR-MALDI for this purpose, as well as for a number of related analytical and thin-film applications.

Authors:
Publication Date:
Research Org.:
Vanderbilt University (US)
Sponsoring Org.:
(US)
OSTI Identifier:
799248
Report Number(s):
DOE/ER/62710
TRN: US0204947
DOE Contract Number:  
FG07-98ER62710
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: 6 Aug 2002
Country of Publication:
United States
Language:
English
Subject:
12 MANAGEMENT OF RADIOACTIVE WASTES, AND NON-RADIOACTIVE WASTES FROM NUCLEAR FACILITIES; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; BENZENE; CALIBRATION STANDARDS; CROWN ETHERS; DESORPTION; FREE ELECTRON LASERS; IONIZATION; ORGANIC ACIDS; SODIUM NITRATES; TOLUENE; RADIOACTIVE WASTES; MASS SPECTROSCOPY; INFRARED RADIATION; PATTERN RECOGNITION

Citation Formats

Richard Haglund Jr. Mass Spectrometric Fingerprinting of Tank Waste Using Tunable, Ultrafast Infrared Lasers. United States: N. p., 2002. Web. doi:10.2172/799248.
Richard Haglund Jr. Mass Spectrometric Fingerprinting of Tank Waste Using Tunable, Ultrafast Infrared Lasers. United States. doi:10.2172/799248.
Richard Haglund Jr. Tue . "Mass Spectrometric Fingerprinting of Tank Waste Using Tunable, Ultrafast Infrared Lasers". United States. doi:10.2172/799248. https://www.osti.gov/servlets/purl/799248.
@article{osti_799248,
title = {Mass Spectrometric Fingerprinting of Tank Waste Using Tunable, Ultrafast Infrared Lasers},
author = {Richard Haglund Jr.},
abstractNote = {The principal scientific thrust of this project was to demonstrate a novel method for precision matrix-assisted laser desorption-ionization (MALDI) mass spectrometry (MS) of model tank-waste materials using, using the sodium nitrate component of the tank waste both as the matrix and as an internal calibration standard. Conventional nanosecond and femtosecond single-frequency lasers and a tunable, mid-infrared free-electron laser were used in the development of the MS protocols and in measurements of the MALDI dynamics. In addition to developing a model of the processes which lead to efficient desorption and ionization of organic molecules (e.g., toluene, benzene, chelators, various organic acids, crown ethers) from sodium nitrate, we developed protocols for quantitative analysis based on the use of the sodium nitrate in tank waste as an internal standard. Comparisons of MALDI-MS using nanosecond and picosecond lasers, and of infrared and ultraviolet lasers, have been especially instructive, and demonstrate the superior potential of IR-MALDI for this purpose, as well as for a number of related analytical and thin-film applications.},
doi = {10.2172/799248},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 06 00:00:00 EDT 2002},
month = {Tue Aug 06 00:00:00 EDT 2002}
}

Technical Report:

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