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Title: Structure and function of cytochrome bc complexes

Abstract

The cytochrome bc complexes represent a phylogenetically diverse group of electron-transfer membrane protein complexes, most familiarly represented by the mitochondrial and bacterial bc1 complexes and the chloroplast and cyanobacterial b6f complex. All these complexes couple electron transfer to protein translocation across a closed lipid bilayer membrane, conserving the free energy released by the oxidation-reduction process in the form of an electrochemical proton gradient across the membrane. Recent exciting developments include the application of site-directed mutagenesis to define the role of conserved residues, and the emergence over the past 5 years of x-ray structures for several mitochondrial complexes, and for two important domains of the b6f complex.

Authors:
; ; ;
Publication Date:
Research Org.:
Lawrence Berkeley National Lab., CA (US)
Sponsoring Org.:
National Institutes of Health (US)
OSTI Identifier:
773775
Report Number(s):
LBNL-44541
R&D Project: 871518; TRN: US0100817
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Journal Article
Journal Name:
Annual Reviews of Biochemistry
Additional Journal Information:
Journal Volume: 69; Other Information: PBD: 1 May 2000
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; CHLOROPLASTS; CYTOCHROMES; ELECTRON TRANSFER; FREE ENERGY; LIPIDS; MUTAGENESIS; PROTEINS; PROTONS; RESIDUES; TRANSLOCATION; BIOLOGICAL ENERGY METABOLISM MITOCHONDRIA CYTOCHROME BC1

Citation Formats

Berry, E.A., Guergova-Kuras, M., Huang, Li-Shar, and Crofts, A.R. Structure and function of cytochrome bc complexes. United States: N. p., 2000. Web. doi:10.1146/annurev.biochem.69.1.1005.
Berry, E.A., Guergova-Kuras, M., Huang, Li-Shar, & Crofts, A.R. Structure and function of cytochrome bc complexes. United States. doi:10.1146/annurev.biochem.69.1.1005.
Berry, E.A., Guergova-Kuras, M., Huang, Li-Shar, and Crofts, A.R. Mon . "Structure and function of cytochrome bc complexes". United States. doi:10.1146/annurev.biochem.69.1.1005.
@article{osti_773775,
title = {Structure and function of cytochrome bc complexes},
author = {Berry, E.A. and Guergova-Kuras, M. and Huang, Li-Shar and Crofts, A.R.},
abstractNote = {The cytochrome bc complexes represent a phylogenetically diverse group of electron-transfer membrane protein complexes, most familiarly represented by the mitochondrial and bacterial bc1 complexes and the chloroplast and cyanobacterial b6f complex. All these complexes couple electron transfer to protein translocation across a closed lipid bilayer membrane, conserving the free energy released by the oxidation-reduction process in the form of an electrochemical proton gradient across the membrane. Recent exciting developments include the application of site-directed mutagenesis to define the role of conserved residues, and the emergence over the past 5 years of x-ray structures for several mitochondrial complexes, and for two important domains of the b6f complex.},
doi = {10.1146/annurev.biochem.69.1.1005},
journal = {Annual Reviews of Biochemistry},
number = ,
volume = 69,
place = {United States},
year = {2000},
month = {5}
}