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Title: Receptor-targeted metalloradiopharmaceuticals. Final technical report

Abstract

Copper (II) and platinum (II) coordination complexes were prepared and characterized. These complexes were designed to afford structural homology with steroidal and non-steroidal estrogens for possible use as receptor-targeted radiopharmaceuticals. While weak affinity for the estrogen receptor was detectable, none would appear to have sufficient receptor-affinity for estrogen-receptor-targeted imaging or therapy.

Authors:
Publication Date:
Research Org.:
Purdue Research Foundation, West Lafayette, Indiana, USA (US)
Sponsoring Org.:
USDOE Office of Energy Research (ER) (US)
OSTI Identifier:
765624
DOE Contract Number:  
FG02-97ER62340
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: 22 Mar 2000
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AFFINITY; COPPER; ESTROGENS; PLATINUM; RADIOPHARMACEUTICALS; THERAPY

Citation Formats

Green, Mark A. Receptor-targeted metalloradiopharmaceuticals. Final technical report. United States: N. p., 2000. Web. doi:10.2172/765624.
Green, Mark A. Receptor-targeted metalloradiopharmaceuticals. Final technical report. United States. doi:10.2172/765624.
Green, Mark A. Wed . "Receptor-targeted metalloradiopharmaceuticals. Final technical report". United States. doi:10.2172/765624. https://www.osti.gov/servlets/purl/765624.
@article{osti_765624,
title = {Receptor-targeted metalloradiopharmaceuticals. Final technical report},
author = {Green, Mark A.},
abstractNote = {Copper (II) and platinum (II) coordination complexes were prepared and characterized. These complexes were designed to afford structural homology with steroidal and non-steroidal estrogens for possible use as receptor-targeted radiopharmaceuticals. While weak affinity for the estrogen receptor was detectable, none would appear to have sufficient receptor-affinity for estrogen-receptor-targeted imaging or therapy.},
doi = {10.2172/765624},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {3}
}