U.S. Department of EnergyOffice of Scientific and Technical Information
14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)
Abstract
Radiocarbon determinations have been obtained on {gamma}-carboxyglutamic acid [Gla] and {alpha}-carboxyglycine (aminomalonate) [Am] as well as acid- and base-hydrolyzed total amino acids isolated from a series of fossil bones. As far as they are aware, Am has not been reported previously in fossil bone and neither Gla nor Am {sup 14}C values have been measured previously. Interest in Gla, an amino acid found in the non-collagen proteins osteocalcin and matrix Gla-protein (MGP), proceeds from the suggestion that it may be preferentially retained and more resistant to diagenetic contamination affecting {sup 14}C values in bones exhibiting low and trace amounts of collagen. The data do not support these suggestions. The suite of bones examined showed a general tendency for total amino acid and Gla concentrations to decrease in concert. Even for bones retaining significant amounts of collagen, Gla (and Am extracts) can yield {sup 14}C values discordant with their expected age and with {sup 14}C values obtained on total amino-acid fractions isolated from the same bone sample.
- Authors:
- Publication Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE Office of Defense Programs (DP) (US)
- OSTI Identifier:
- 757416
- Report Number(s):
- UCRL-JC-134031; YN0100000
YN0100000; TRN: AH200123%%482
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Conference
- Resource Relation:
- Conference: 16th International 14C Conference, Gronningen (NL), 06/16/1997--06/21/1997; Other Information: PBD: 27 Apr 1999
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; AGE ESTIMATION; AMINO ACIDS; COLLAGEN; CONTAMINATION; PROTEINS; TRACE AMOUNTS; CARBON 14
Citation Formats
Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, and Hare, P E. 14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate). United States: N. p., 1999.
Web.
Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, & Hare, P E. 14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate). United States.
Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, and Hare, P E. 1999.
"14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)". United States. https://www.osti.gov/servlets/purl/757416.
@article{osti_757416,
title = {14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)},
author = {Southon, J R and Burky, R T and Kirner, D L and Taylor, R E and Hare, P E},
abstractNote = {Radiocarbon determinations have been obtained on {gamma}-carboxyglutamic acid [Gla] and {alpha}-carboxyglycine (aminomalonate) [Am] as well as acid- and base-hydrolyzed total amino acids isolated from a series of fossil bones. As far as they are aware, Am has not been reported previously in fossil bone and neither Gla nor Am {sup 14}C values have been measured previously. Interest in Gla, an amino acid found in the non-collagen proteins osteocalcin and matrix Gla-protein (MGP), proceeds from the suggestion that it may be preferentially retained and more resistant to diagenetic contamination affecting {sup 14}C values in bones exhibiting low and trace amounts of collagen. The data do not support these suggestions. The suite of bones examined showed a general tendency for total amino acid and Gla concentrations to decrease in concert. Even for bones retaining significant amounts of collagen, Gla (and Am extracts) can yield {sup 14}C values discordant with their expected age and with {sup 14}C values obtained on total amino-acid fractions isolated from the same bone sample.},
doi = {},
url = {https://www.osti.gov/biblio/757416},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 27 00:00:00 EDT 1999},
month = {Tue Apr 27 00:00:00 EDT 1999}
}