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Title: 14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)

Abstract

Radiocarbon determinations have been obtained on {gamma}-carboxyglutamic acid [Gla] and {alpha}-carboxyglycine (aminomalonate) [Am] as well as acid- and base-hydrolyzed total amino acids isolated from a series of fossil bones. As far as they are aware, Am has not been reported previously in fossil bone and neither Gla nor Am {sup 14}C values have been measured previously. Interest in Gla, an amino acid found in the non-collagen proteins osteocalcin and matrix Gla-protein (MGP), proceeds from the suggestion that it may be preferentially retained and more resistant to diagenetic contamination affecting {sup 14}C values in bones exhibiting low and trace amounts of collagen. The data do not support these suggestions. The suite of bones examined showed a general tendency for total amino acid and Gla concentrations to decrease in concert. Even for bones retaining significant amounts of collagen, Gla (and Am extracts) can yield {sup 14}C values discordant with their expected age and with {sup 14}C values obtained on total amino-acid fractions isolated from the same bone sample.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Lawrence Livermore National Lab., CA (US)
Sponsoring Org.:
USDOE Office of Defense Programs (DP) (US)
OSTI Identifier:
757416
Report Number(s):
UCRL-JC-134031; YN0100000
YN0100000; TRN: AH200123%%482
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Conference
Resource Relation:
Conference: 16th International 14C Conference, Gronningen (NL), 06/16/1997--06/21/1997; Other Information: PBD: 27 Apr 1999
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; AGE ESTIMATION; AMINO ACIDS; COLLAGEN; CONTAMINATION; PROTEINS; TRACE AMOUNTS; CARBON 14

Citation Formats

Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, and Hare, P E. 14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate). United States: N. p., 1999. Web.
Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, & Hare, P E. 14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate). United States.
Southon, J R, Burky, R T, Kirner, D L, Taylor, R E, and Hare, P E. Tue . "14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)". United States. https://www.osti.gov/servlets/purl/757416.
@article{osti_757416,
title = {14C dating of bone using (gamma) Carboxyglutamic Acid and Carboxyglycine (Aminomalonate)},
author = {Southon, J R and Burky, R T and Kirner, D L and Taylor, R E and Hare, P E},
abstractNote = {Radiocarbon determinations have been obtained on {gamma}-carboxyglutamic acid [Gla] and {alpha}-carboxyglycine (aminomalonate) [Am] as well as acid- and base-hydrolyzed total amino acids isolated from a series of fossil bones. As far as they are aware, Am has not been reported previously in fossil bone and neither Gla nor Am {sup 14}C values have been measured previously. Interest in Gla, an amino acid found in the non-collagen proteins osteocalcin and matrix Gla-protein (MGP), proceeds from the suggestion that it may be preferentially retained and more resistant to diagenetic contamination affecting {sup 14}C values in bones exhibiting low and trace amounts of collagen. The data do not support these suggestions. The suite of bones examined showed a general tendency for total amino acid and Gla concentrations to decrease in concert. Even for bones retaining significant amounts of collagen, Gla (and Am extracts) can yield {sup 14}C values discordant with their expected age and with {sup 14}C values obtained on total amino-acid fractions isolated from the same bone sample.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {4}
}

Conference:
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