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Title: Systematic errors in gas chromatography: mass spectrometry isotope ratio measurements. [Mass cycling error]

Abstract

The mass cycling error, a systematic bias inherent in isotope ratio measurements carried out by switching ion beams which are time-variable, is systematically explored in a series of trial calculations, and the validity of these calculations is demonstrated experimentally using a typical gas chromatography-mass spectrometry system. The effects of varying measurement conditions are considered in terms of chromatographic peak profiles, relative ion-beam integration times, delays required for ion-beam positioning, unidirectional vs. bidirectional scanning patterns, and chromatographic fractionation of the isotopes. It is concluded that the unidirectional scanning pattern (ABCABC...) is superior to the bidirectional pattern (ABCCBA...), and that, in the absence of chromatographic fractionation of the isotopes, a bias of less than 1 percent can be obtained by its use for ten or more cycles on any given gas chromatographic peak. Under these same conditions, 35 or more observation cycles are required to bring the bias below 0.1 percent.

Authors:
;
Publication Date:
Research Org.:
Indiana Univ., Bloomington
OSTI Identifier:
7353335
Resource Type:
Journal Article
Journal Name:
Anal. Chem.; (United States)
Additional Journal Information:
Journal Volume: 48:9
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; GAS CHROMATOGRAPHY; ERRORS; ISOTOPE RATIO; MASS SPECTROSCOPY; ACCURACY; ELECTRON MULTIPLIER DETECTORS; ION BEAMS; MEASURING METHODS; STATISTICS; BEAMS; CHROMATOGRAPHY; MATHEMATICS; MEASURING INSTRUMENTS; RADIATION DETECTORS; SEPARATION PROCESSES; SPECTROSCOPY; 400104* - Spectral Procedures- (-1987); 400105 - Separation Procedures

Citation Formats

Matthews, D E, and Hayes, J M. Systematic errors in gas chromatography: mass spectrometry isotope ratio measurements. [Mass cycling error]. United States: N. p., 1976. Web. doi:10.1021/ac50003a028.
Matthews, D E, & Hayes, J M. Systematic errors in gas chromatography: mass spectrometry isotope ratio measurements. [Mass cycling error]. United States. https://doi.org/10.1021/ac50003a028
Matthews, D E, and Hayes, J M. 1976. "Systematic errors in gas chromatography: mass spectrometry isotope ratio measurements. [Mass cycling error]". United States. https://doi.org/10.1021/ac50003a028.
@article{osti_7353335,
title = {Systematic errors in gas chromatography: mass spectrometry isotope ratio measurements. [Mass cycling error]},
author = {Matthews, D E and Hayes, J M},
abstractNote = {The mass cycling error, a systematic bias inherent in isotope ratio measurements carried out by switching ion beams which are time-variable, is systematically explored in a series of trial calculations, and the validity of these calculations is demonstrated experimentally using a typical gas chromatography-mass spectrometry system. The effects of varying measurement conditions are considered in terms of chromatographic peak profiles, relative ion-beam integration times, delays required for ion-beam positioning, unidirectional vs. bidirectional scanning patterns, and chromatographic fractionation of the isotopes. It is concluded that the unidirectional scanning pattern (ABCABC...) is superior to the bidirectional pattern (ABCCBA...), and that, in the absence of chromatographic fractionation of the isotopes, a bias of less than 1 percent can be obtained by its use for ten or more cycles on any given gas chromatographic peak. Under these same conditions, 35 or more observation cycles are required to bring the bias below 0.1 percent.},
doi = {10.1021/ac50003a028},
url = {https://www.osti.gov/biblio/7353335}, journal = {Anal. Chem.; (United States)},
number = ,
volume = 48:9,
place = {United States},
year = {Sun Aug 01 00:00:00 EDT 1976},
month = {Sun Aug 01 00:00:00 EDT 1976}
}