The gene for creatine kinase, mitochondrial 2 (sarcomeric; CKMT2), maps to chromosome 5q13. 3

Journal Article · Fri Oct 01 00:00:00 EDT 1993 · Genomics; (United States)

DOI:https://doi.org/10.1006/geno.1993.1437· OSTI ID:7199960

Richard, I; Devaud, C ^[1]; Cherif, D; Cohen, D; Beckmann, J S ^[2]

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1. GENETHON, Evry (France)
2. Centre d'Etude du Polymorphisme Humain, Paris (France)

YAC clones for the creatine kinase, mitochrondial 2 (sarcomeric; CKMT2), gene were isolated. One of these YACs was localized on chromosome 5q13.3 by fluorescence in situ hybridization. A polymorphic dinucleotide repeat (heterozygosity 0.77) was identified within the seventh intron of the CKMT2 gene. Genotyping of CEPH families allowed positioning of CKMT2 on the multipoint map of chromosome 5 between D5S424 and D5S428, distal to spinal muscular atrophy (SMA) (5q12-q14). 8 refs., 1 fig., 2 tabs.

• OSTI ID: 7199960
• Journal Information: Genomics; (United States), Vol. 18:1; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
CREATINE
PHOSPHORYLATION
HUMAN CHROMOSOME 5
GENETIC MAPPING
PHOSPHOTRANSFERASES
GENES
AMINO ACIDS
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
CHROMOSOMES
ENZYMES
HUMAN CHROMOSOMES
MAPPING
ORGANIC ACIDS
ORGANIC COMPOUNDS
PHOSPHORUS-GROUP TRANSFERASES
PROTEINS
TRANSFERASES
550400* - Genetics