skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Studies on trypsin-like enzymes in sperm and early embryos

Abstract

Results are reported from a study of acrosomal proteinase, a trypsin-like enzyme (TLE), found in the acrosome of all eutherian mammals studied to date. It has been implicated in the dissolution of a passage for the sperm through the zona pellucida of the egg, a step necessary for in vivo fertilization. A cytochemical procedure employing autoradiographic film as a gelatin substrate is described for in situ detection and localization of acrosomal proteolytic activity. A role for TLE in the early development of embryos is suggested. (CH)

Authors:
Publication Date:
Research Org.:
California Univ., Livermore (USA). Lawrence Livermore Lab.
OSTI Identifier:
7190403
Report Number(s):
UCRL-52040
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Technical Report
Resource Relation:
Other Information: Thesis
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; ENZYMES; BIOCHEMICAL REACTION KINETICS; SPERMATOZOA; MAMMALS; EMBRYOS; IN VITRO; ANIMALS; GAMETES; GERM CELLS; KINETICS; REACTION KINETICS; VERTEBRATES; 550200* - Biochemistry

Citation Formats

Penn, A. Studies on trypsin-like enzymes in sperm and early embryos. United States: N. p., 1975. Web.
Penn, A. Studies on trypsin-like enzymes in sperm and early embryos. United States.
Penn, A. Tue . "Studies on trypsin-like enzymes in sperm and early embryos". United States.
@article{osti_7190403,
title = {Studies on trypsin-like enzymes in sperm and early embryos},
author = {Penn, A.},
abstractNote = {Results are reported from a study of acrosomal proteinase, a trypsin-like enzyme (TLE), found in the acrosome of all eutherian mammals studied to date. It has been implicated in the dissolution of a passage for the sperm through the zona pellucida of the egg, a step necessary for in vivo fertilization. A cytochemical procedure employing autoradiographic film as a gelatin substrate is described for in situ detection and localization of acrosomal proteolytic activity. A role for TLE in the early development of embryos is suggested. (CH)},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1975},
month = {12}
}

Technical Report:
Other availability
Please see Document Availability for additional information on obtaining the full-text document. Library patrons may search WorldCat to identify libraries that may hold this item. Keep in mind that many technical reports are not cataloged in WorldCat.

Save / Share: