Enzymatic temperature change indicator

Klibanov, A M; Dordick, J S

Title: Enzymatic temperature change indicator

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Abstract

A temperature change indicator is described which is composed of an enzyme and a substrate for that enzyme suspended in a solid organic solvent or mixture of solvents as a support medium. The organic solvent or solvents are chosen so as to melt at a specific temperature or in a specific temperature range. When the temperature of the indicator is elevated above the chosen, or critical temperature, the solid organic solvent support will melt, and the enzymatic reaction will occur, producing a visually detectable product which is stable to further temperature variation. 1 fig.

Inventors:: Klibanov, A M; Dordick, J S

Publication Date:: Tue May 02 00:00:00 EDT 1989

OSTI Identifier:: 7164620

Patent Number(s):: US 4826762; A

Application Number:: CNN: 957381; PPN: US 7-112893

Assignee:: Massachusetts Inst. of Tech., Cambridge, MA (United States)

Resource Type:: Patent

Resource Relation:: Patent File Date: 23 Oct 1987

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION; ENZYMES; PERFORMANCE; PHASE CHANGE MATERIALS; TEMPERATURE MEASUREMENT; CHEMICAL REACTIONS; TRANSITION TEMPERATURE; MATERIALS; ORGANIC COMPOUNDS; PHYSICAL PROPERTIES; PROTEINS; THERMODYNAMIC PROPERTIES; 440500* - Thermal Instrumentation- (1990-)

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                    Klibanov, A M, and Dordick, J S. Enzymatic temperature change indicator.  United States: N. p., 1989. 
        Web.

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                    Klibanov, A M, & Dordick, J S. Enzymatic temperature change indicator.  United States.

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                    Klibanov, A M, and Dordick, J S. 1989.  
        "Enzymatic temperature change indicator".  United States.

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@article{osti_7164620,

  title        = {Enzymatic temperature change indicator},

  author       = {Klibanov, A M and Dordick, J S},

  abstractNote = {A temperature change indicator is described which is composed of an enzyme and a substrate for that enzyme suspended in a solid organic solvent or mixture of solvents as a support medium. The organic solvent or solvents are chosen so as to melt at a specific temperature or in a specific temperature range. When the temperature of the indicator is elevated above the chosen, or critical temperature, the solid organic solvent support will melt, and the enzymatic reaction will occur, producing a visually detectable product which is stable to further temperature variation. 1 fig.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/7164620},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue May 02 00:00:00 EDT 1989},

  month        = {Tue May 02 00:00:00 EDT 1989}

}

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