Synthesis of alpha-amino acids

Patent · Tue Jan 25 00:00:00 EST 1983

OSTI ID:7145019

Davis, Jr, J W

A method is described for synthesizing alpha amino acids proceeding through novel intermediates of the formulas: R[sub 1]R[sub 2]C(OSOCl)CN, R[sub 1]R[sub 2]C(Cl)CN and [R[sub 1]R[sub 2]C(CN)O][sub 2]SO wherein R[sub 1] and R[sub 2] are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 10 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art. No Drawings

• DOE Contract Number: W-7405-ENG-48
• Assignee: Secretary of Energy, Washington, DC (United States)
• Patent Number(s): US 4370493; A
• Application Number: PPN: US 6-278106
• OSTI ID: 7145019
• Resource Relation: Patent File Date: 29 Jun 1981
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
AMINO ACIDS
SYNTHESIS
BIOCHEMISTRY
CHEMICAL BONDS
CHEMICAL COMPOSITION
CARBOXYLIC ACIDS
CHEMISTRY
ORGANIC ACIDS
ORGANIC COMPOUNDS
550200* - Biochemistry