Genetic control of x-ray resistance in budding yeast cells

Journal Article · Sat Jan 01 00:00:00 EST 1977 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3574521· OSTI ID:7122319

Benathen, I A; Beam, C A

Five x-ray-sensitive mutants were selected from 10,000 colonies arising from survivors of ultraviolet light. These were named XS5, XS6, XS7, XS8, and XS9. Mutant XS1 was donated by Nakai. These mutations affect the resistant budding cell survival component of the survival curve and, in diploids, the low-dose interdivisional cell shoulder. They are of two types: Class I, in which budding cells lack resistance; and Class II, in which budding cells show reduced resistance. When crossed with one another, they show a complex complementation pattern. Gene dosage effects are seen in XS1 heterozygotes, while budding but not between divisions. No direct correlation between radiation sensitivity, meiosis, and sporulation is observed; genes which influence radiation sensitivity do not affect meiotic recombination. A single mutation (XS1 or XS5) suppresses the shoulders of the survival curves of both budding haploid cells and diploid nonbudding cells.

• Research Organization: Brooklyn Coll.
• OSTI ID: 7122319
• Journal Information: Radiat. Res.; (United States), Vol. 69:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
YEASTS
MUTANTS
RADIOSENSITIVITY
BIOLOGICAL RADIATION EFFECTS
CONTROL
GENES
MUTATIONS
X RADIATION
BIOLOGICAL EFFECTS
BIOMASS
ELECTROMAGNETIC RADIATION
ENERGY SOURCES
FUNGI
IONIZING RADIATIONS
MICROORGANISMS
PLANTS
RADIATION EFFECTS
RADIATIONS
RENEWABLE ENERGY SOURCES
560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)