In-vivo measurements of Pb-210 to determine cumulative exposure to radon daughters: A pilot study

Technical Report · Wed May 01 00:00:00 EDT 1991

DOI:https://doi.org/10.2172/7114397· OSTI ID:7114397

Laurer, G R; Cohen, N ^[1]; Stark, A; Ju, C ^[2]

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1. New York Univ. Medical Center, Tuxedo, NY (United States). Dept. of Environmental Medicine
2. New York State Dept. of Health, Albany, NY (United States). Bureau of Environmental and Occupational Epidemiology

The objective of this study is to demonstrate the feasibility of estimating cumulative exposure of individuals to low concentrations of radon by measuring the amount of Pb-A-10 in their skeletons. This report presents progress to date establishing the validity of an vivo technique to measure skeletal burdens of Pb-210, accumulated from exposure to radon and radon progeny. With the skeletal content of Pb--210 and a model for Pb metabolism, cumulative exposure to radon and its short-lived daughters (radon/daughters) may be calculated for use in deriving a dose-response relationship between lung cancer and exposure to radon/daughters. Data are presented for 29 subjects exposed to above-average'' radon concentrations in their homes, showing the correlation between measured Pb--210 burdens, and measured pCi/l and WLM exposure estimates. Their results are compared to measurements of a population of 24 subject's presumed exposed to average concentrations. Measurements of a Pennsylvania family exposed for a year in a home with an extremely high radon content are also presented. Update of results of an ongoing study of the biological half-time of Pb--210 in man involving measurements, of a retired radiation worker with a 40 year old skeletal burden of Pb-210.

• Research Organization: New York Univ. Medical Center, Tuxedo, NY (United States). Dept. of Environmental Medicine; New York State Dept. of Health, Albany, NY (United States). Bureau of Environmental and Occupational Epidemiology
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: FG02-90ER60944
• OSTI ID: 7114397
• Report Number(s): DOE/ER/60944-2; ON: DE92017389
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LEAD 210
DOSIMETRY
OCCUPANTS
RADIATION DOSES
CHRONIC EXPOSURE
DAUGHTER PRODUCTS
INDOOR AIR POLLUTION
MINES
PENNSYLVANIA
PROGRESS REPORT
RADON
REGRESSION ANALYSIS
RESIDENTIAL BUILDINGS
SKELETON
AIR POLLUTION
ALPHA DECAY RADIOISOTOPES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BUILDINGS
DEVELOPED COUNTRIES
DOCUMENT TYPES
DOSES
ELEMENTS
EVEN-EVEN NUCLEI
FLUIDS
GASES
HEAVY NUCLEI
ISOTOPES
LEAD ISOTOPES
MATHEMATICS
NONMETALS
NORTH AMERICA
NUCLEI
ORGANS
POLLUTION
RADIOISOTOPES
RARE GASES
STATISTICS
UNDERGROUND FACILITIES
USA
YEARS LIVING RADIOISOTOPES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man