A transducin-like gene maps to the autosomal dominant polycystic kidney disease gene region
Journal Article
·
· Genomics; (United States)
- Yale Univ. School of Medicine, New Haven, CT (United States)
A novel human gene (sazD) that maps to the autosomal dominant polycystic kidney disease region shares sequence similarity with members of the [beta]-transducin superfamily. The cDNA sazD-c predicts an [approximately]58-kDa protein (sazD) with seven internal repeats, similar to the WD-40 motif of the transducin family. The size of this protein family has been expanding rapidly; however, neither the structure nor the function of this repeated motif is known. Preliminary data do not suggest that sazD is mutated in patients with polycystic kidney disease. 13 refs., 2 figs.
- OSTI ID:
- 7076074
- Journal Information:
- Genomics; (United States), Vol. 18:3; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
Similar Records
Identification of the autosomal dominant polycystic kidney disease gene, PKD1
Autosomal Dominant Polycystic Kidney Disease (ADPKD) in an Italian family carrying a novel nonsense mutation and two missense changes in exons 44 and 45 of the PKD1 gene
Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1)
Journal Article
·
Thu Sep 01 00:00:00 EDT 1994
· American Journal of Human Genetics
·
OSTI ID:7076074
Autosomal Dominant Polycystic Kidney Disease (ADPKD) in an Italian family carrying a novel nonsense mutation and two missense changes in exons 44 and 45 of the PKD1 gene
Journal Article
·
Wed Oct 16 00:00:00 EDT 1996
· American Journal of Medical Genetics
·
OSTI ID:7076074
Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1)
Journal Article
·
Mon Aug 01 00:00:00 EDT 1994
· American Journal of Human Genetics; (United States)
·
OSTI ID:7076074
+7 more