Motion corrected hepatic scintigraphy: an objective clinical evaluation. [/sup 99m/Tc tracer technique]
An analogue motion-correction device was built for a scintillation camera. Corrected and uncorrected images were simultaneously recorded on Polaroid film during routine hepatic scintigraphy of 1100 patients, selected without known bias. Autopsy, liver biopsy or inspection at laparotomy (and clinical followup in three patients with neither known malignancy nor benign liver disease) were considered to have established the true state of the livers of 49 patients with hepatic masses and 53 patients with normal livers. Five observers of varying experience in nuclear medicine independently evaluated the scintigrams for the presence of mass lesions, using a five-category rating scale, without knowledge of the true states. Results were expressed as receiver operating characteristic curves. For each observer, performance was better with motion correction, or when interpreting corrected and uncorrected studies together, than when reading the uncorrected studies alone. Analogue motion correction is an effective, inexpensive method for improving hepatic scintigraphy with a scintillation camera. The degree to which motion correction improves the detectability of mass lesions is a function of the size of the lesions, the performance parameters of the imaging system and the display medium, the depth of the subject's respirations, the counting rate, and the count density of the image, as well as of the proper adjustment of the motion-correction device itself.
- Research Organization:
- Rush-Presbyterian-St. Luke's Medical Center, Chicago
- OSTI ID:
- 7075990
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 19:2
- Country of Publication:
- United States
- Language:
- English
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LIVER
SCINTISCANNING
EVALUATION
TECHNETIUM 99
AUTOPSY
BIOPSY
ISOMERIC NUCLEI
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics