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Title: Nuclear Medicine Program progress report for quarter ending March 31, 1990

Abstract

The evaluation of the effects of albumin and albumin plus sodium palmitate in the phosphate buffer perfusate on the relative incorporation of 15-(p-(I-125)iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) into endogenous lipids of isolated rat hearts has been studied. The effects of eluant salt character and concentration on the elution of (Re-188)perrhenate from the alumina-based tungsten-188/rhenium-188 generator system have also been investigated. During this period several agents were supplied to Medical Cooperative investigators, including (I-123)-labeled and (I-131)-labeled fatty acid analogues for studies at the Brookhaven National Laboratory and the Cardiology Department at the Free University of Amsterdam. Tungsten-188/rhenium-188 generators were supplied to the University of Massachusetts and the Center for Molecular Medicine and Immunology, in Newark, New Jersey. Osmium-191 was supplied for fabrication of generators for patient studies in Finland. 1 ref., 2 figs., 2 tabs.

Authors:
; ; ; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Oak Ridge National Lab., TN (USA)
Sponsoring Org.:
DOE/ER
OSTI Identifier:
7015943
Report Number(s):
ORNL/TM-11550
ON: DE90013608
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; ALBUMINS; BIOLOGICAL EFFECTS; MONOCARBOXYLIC ACIDS; IODINATION; RADIOPHARMACEUTICALS; SYNTHESIS; ABSORPTIVITY; ANTIBODIES; AQUEOUS SOLUTIONS; CHELATING AGENTS; HEART; IODINE 123; IODINE 131; NUCLEAR MEDICINE; PROGRESS REPORT; RADIOCHEMISTRY; RATS; RHENIUM 188; TUNGSTEN 188; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR SYSTEM; CHEMICAL REACTIONS; CHEMISTRY; DAYS LIVING RADIOISOTOPES; DISPERSIONS; DOCUMENT TYPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; HALOGENATION; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; MIXTURES; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; OPTICAL PROPERTIES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PHYSICAL PROPERTIES; PROTEINS; RADIOISOTOPES; RHENIUM ISOTOPES; RODENTS; SOLUTIONS; TUNGSTEN ISOTOPES; VERTEBRATES; 550600* - Medicine; 550500 - Metabolism

Citation Formats

Knapp, Jr, F F, Ambrose, K R, Callahan, A P, Alfred, J F, Hasan, A, Lambert, C R, McPherson, D W, Mirzadeh, S, Srivastava, P C, Lambert, S J, and Rice, D E. Nuclear Medicine Program progress report for quarter ending March 31, 1990. United States: N. p., 1990. Web.
Knapp, Jr, F F, Ambrose, K R, Callahan, A P, Alfred, J F, Hasan, A, Lambert, C R, McPherson, D W, Mirzadeh, S, Srivastava, P C, Lambert, S J, & Rice, D E. Nuclear Medicine Program progress report for quarter ending March 31, 1990. United States.
Knapp, Jr, F F, Ambrose, K R, Callahan, A P, Alfred, J F, Hasan, A, Lambert, C R, McPherson, D W, Mirzadeh, S, Srivastava, P C, Lambert, S J, and Rice, D E. Sun . "Nuclear Medicine Program progress report for quarter ending March 31, 1990". United States.
@article{osti_7015943,
title = {Nuclear Medicine Program progress report for quarter ending March 31, 1990},
author = {Knapp, Jr, F F and Ambrose, K R and Callahan, A P and Alfred, J F and Hasan, A and Lambert, C R and McPherson, D W and Mirzadeh, S and Srivastava, P C and Lambert, S J and Rice, D E},
abstractNote = {The evaluation of the effects of albumin and albumin plus sodium palmitate in the phosphate buffer perfusate on the relative incorporation of 15-(p-(I-125)iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) into endogenous lipids of isolated rat hearts has been studied. The effects of eluant salt character and concentration on the elution of (Re-188)perrhenate from the alumina-based tungsten-188/rhenium-188 generator system have also been investigated. During this period several agents were supplied to Medical Cooperative investigators, including (I-123)-labeled and (I-131)-labeled fatty acid analogues for studies at the Brookhaven National Laboratory and the Cardiology Department at the Free University of Amsterdam. Tungsten-188/rhenium-188 generators were supplied to the University of Massachusetts and the Center for Molecular Medicine and Immunology, in Newark, New Jersey. Osmium-191 was supplied for fabrication of generators for patient studies in Finland. 1 ref., 2 figs., 2 tabs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1990},
month = {7}
}

Technical Report:
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