skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Separation of oxygen isotopic benzoic acids by capillary zone electrophoresis based on isotope effects on the dissociation of the carboxyl group

Abstract

Oxygen isotopic benzoic acids are chosen as examples of closely related compounds for the study of ultrahigh-resolution separation by capillary zone electrophoresis (CZE). Optimum conditions for the separation of acids having slightly different dissociation constants are theoretically discussed on the basis of the resolution equation in CZE. The effects of the following factors on the resolution have been experimentally investigated: applied voltages, capillary tube lengths, pH of the buffers, and electroosmotic velocities. Three isotopic acids, C/sub 6/H/sub 5/C/sup 16/O/sub 2/H, C/sub 6/H/sub 5/C/sup 16/O/sup 18/OH, and C/sub 6/H/sub 5/C/sup 18/O/sub 2/H, have been successfully separated in 100 min under the optimum conditions.

Authors:
; ; ;
Publication Date:
Research Org.:
Kyoto Univ. (Japan)
OSTI Identifier:
7012576
Resource Type:
Journal Article
Journal Name:
Anal. Chem.; (United States)
Additional Journal Information:
Journal Volume: 60:17
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; BENZOIC ACID; ELECTROPHORESIS; OXYGEN 16; ISOTOPE SEPARATION; OXYGEN 18; CAPILLARIES; ELECTRIC POTENTIAL; EXPERIMENTAL DATA; ISOTOPE EFFECTS; PH VALUE; VELOCITY; BLOOD VESSELS; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR SYSTEM; DATA; EVEN-EVEN NUCLEI; INFORMATION; ISOTOPES; LIGHT NUCLEI; MONOCARBOXYLIC ACIDS; NUCLEI; NUMERICAL DATA; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; OXYGEN ISOTOPES; SEPARATION PROCESSES; STABLE ISOTOPES; 400202* - Isotope Effects, Isotope Exchange, & Isotope Separation; 400105 - Separation Procedures

Citation Formats

Terabe, S, Yashima, T, Tanaka, N, and Araki, M. Separation of oxygen isotopic benzoic acids by capillary zone electrophoresis based on isotope effects on the dissociation of the carboxyl group. United States: N. p., 1988. Web. doi:10.1021/ac00168a009.
Terabe, S, Yashima, T, Tanaka, N, & Araki, M. Separation of oxygen isotopic benzoic acids by capillary zone electrophoresis based on isotope effects on the dissociation of the carboxyl group. United States. https://doi.org/10.1021/ac00168a009
Terabe, S, Yashima, T, Tanaka, N, and Araki, M. Thu . "Separation of oxygen isotopic benzoic acids by capillary zone electrophoresis based on isotope effects on the dissociation of the carboxyl group". United States. https://doi.org/10.1021/ac00168a009.
@article{osti_7012576,
title = {Separation of oxygen isotopic benzoic acids by capillary zone electrophoresis based on isotope effects on the dissociation of the carboxyl group},
author = {Terabe, S and Yashima, T and Tanaka, N and Araki, M},
abstractNote = {Oxygen isotopic benzoic acids are chosen as examples of closely related compounds for the study of ultrahigh-resolution separation by capillary zone electrophoresis (CZE). Optimum conditions for the separation of acids having slightly different dissociation constants are theoretically discussed on the basis of the resolution equation in CZE. The effects of the following factors on the resolution have been experimentally investigated: applied voltages, capillary tube lengths, pH of the buffers, and electroosmotic velocities. Three isotopic acids, C/sub 6/H/sub 5/C/sup 16/O/sub 2/H, C/sub 6/H/sub 5/C/sup 16/O/sup 18/OH, and C/sub 6/H/sub 5/C/sup 18/O/sub 2/H, have been successfully separated in 100 min under the optimum conditions.},
doi = {10.1021/ac00168a009},
url = {https://www.osti.gov/biblio/7012576}, journal = {Anal. Chem.; (United States)},
number = ,
volume = 60:17,
place = {United States},
year = {1988},
month = {9}
}