State of synapses of the cortex of cerebral hemispheres on gamma-irradiation

Journal Article · Wed Nov 01 00:00:00 EST 1989 · Neuroscience and Behavioral Physiology; (USA)

DOI:https://doi.org/10.1007/BF01181863· OSTI ID:6992349

Gaidamakin, N A; Ushakov, I B

In adult rats with developing neurological disorders we detected destructive changes in most of the synapses of the brain sensorimotor cortex 1.6-4.3 h after a single dose of gamma-irradiation (200 Gy). All functionally important parts on the axonal and dendritic sides of the synapses had undergone changes: mitochondria, synaptic vesicles, pre- and postsynaptic membranes, synaptic complexes, and subsynaptic consolidations, axonal and dendritic plasma, and their inclusions. These changes possibly cause disconnection of the neurons and provide a structural basis for neurological deficiencies following a high substantial ionizing radiation.

• OSTI ID: 6992349
• Journal Information: Neuroscience and Behavioral Physiology; (USA), Vol. 19:6; ISSN 0097-0549
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CEREBRAL CORTEX
BIOLOGICAL RADIATION EFFECTS
NERVOUS SYSTEM DISEASES
RADIOINDUCTION
ACUTE IRRADIATION
CELL MEMBRANES
GAMMA RADIATION
NERVES
RADIATION INJURIES
RATS
ACUTE EXPOSURE
ANIMALS
BIOLOGICAL EFFECTS
BODY
BRAIN
CELL CONSTITUENTS
CENTRAL NERVOUS SYSTEM
CEREBRUM
DISEASES
ELECTROMAGNETIC RADIATION
INJURIES
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MEMBRANES
NERVOUS SYSTEM
ORGANS
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals