Quantitation of size of myocardial infarctions by computerized transmission tomography. Comparison with hot-spot and cold-spot radionuclide scans
The current study evaluated the ability to quantitate the volume of myocardial infarctions when they are outlined by intravenously administered contrast media in the myocardial perfusion phase and in the phase of delayed contrast enhancement of the infarct. Quantitation by contrast media was assessed from computerized transmission tomography (CTT) scans of the ex situ heart and compared with quantitation by technetium-99m (/sup 99m/Tc)pyrophosphate (/sup 99m/Tc PYP) and thallium-201 (201Tl) scans of the same ex situ hearts. True volume was defined by histochemical morphometry. CTT during the contrast perfusion phase uniformly underestimated infarct size but had a good correlation with true volume. CTT during enhancement phase correlated closely with true volume (r . 0.98) and most precisely measured true size (y . 1.06 X 0.23). The /sup 99m/Tc PYP scan overestimated infarct volume (predictive overestimation of 6 to 199%) but had a good correlation with true volume. 201Tl underestimated infarct volume but correlated well with true volume. Thus, quantitation of infarct volume from CTT scans performed during either the perfusion or infarct enhancement phase after intravenous contrast media provides a good estimate of true infarct volume. Delineation of the infarct by contrast media in the ex situ heart is more precise during the phase of delayed enhancement of the infarct.
- OSTI ID:
- 6981912
- Journal Information:
- Invest. Radiol.; (United States), Vol. 18:3
- Country of Publication:
- United States
- Language:
- English
Similar Records
Impact of radionuclide techniques on evaluation of patients with ischemic heart disease
Clinicopathologic findings in 52 patients studied by technetium-99m stannous pyrophosphate myocardial scintigraphy
Related Subjects
DIAGNOSTIC TECHNIQUES
COMPARATIVE EVALUATIONS
HEART
COMPUTERIZED TOMOGRAPHY
RADIOISOTOPE SCANNING
MYOCARDIAL INFARCTION
DIAGNOSIS
CONTRAST MEDIA
ISOMERIC NUCLEI
TECHNETIUM 99
THALLIUM 201
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
TECHNETIUM ISOTOPES
THALLIUM ISOTOPES
TOMOGRAPHY
YEARS LIVING RADIOISOTOPES
550602* - Medicine- External Radiation in Diagnostics- (1980-)
550601 - Medicine- Unsealed Radionuclides in Diagnostics