Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy
Abstract
Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.
- Authors:
-
- Univ. of Utah, School of Medicine, Salt Lake City, UT (United States)
- Publication Date:
- OSTI Identifier:
- 6975546
- Resource Type:
- Journal Article
- Journal Name:
- American Journal of Human Genetics; (United States)
- Additional Journal Information:
- Journal Volume: 54:2; Journal ID: ISSN 0002-9297
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; HUMAN X CHROMOSOME; GENETIC MAPPING; NERVOUS SYSTEM DISEASES; CHROMOSOMES; DISEASES; HETEROCHROMOSOMES; HUMAN CHROMOSOMES; MAPPING; X CHROMOSOME; 550400* - Genetics
Citation Formats
Fain, P R, Barker, D F, and Chance, P F. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy. United States: N. p., 1994.
Web.
Fain, P R, Barker, D F, & Chance, P F. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy. United States.
Fain, P R, Barker, D F, and Chance, P F. 1994.
"Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy". United States.
@article{osti_6975546,
title = {Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy},
author = {Fain, P R and Barker, D F and Chance, P F},
abstractNote = {Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.},
doi = {},
url = {https://www.osti.gov/biblio/6975546},
journal = {American Journal of Human Genetics; (United States)},
issn = {0002-9297},
number = ,
volume = 54:2,
place = {United States},
year = {Tue Feb 01 00:00:00 EST 1994},
month = {Tue Feb 01 00:00:00 EST 1994}
}
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