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Title: Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy

Abstract

Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.

Authors:
; ;  [1]
  1. Univ. of Utah, School of Medicine, Salt Lake City, UT (United States)
Publication Date:
OSTI Identifier:
6975546
Resource Type:
Journal Article
Journal Name:
American Journal of Human Genetics; (United States)
Additional Journal Information:
Journal Volume: 54:2; Journal ID: ISSN 0002-9297
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; HUMAN X CHROMOSOME; GENETIC MAPPING; NERVOUS SYSTEM DISEASES; CHROMOSOMES; DISEASES; HETEROCHROMOSOMES; HUMAN CHROMOSOMES; MAPPING; X CHROMOSOME; 550400* - Genetics

Citation Formats

Fain, P R, Barker, D F, and Chance, P F. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy. United States: N. p., 1994. Web.
Fain, P R, Barker, D F, & Chance, P F. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy. United States.
Fain, P R, Barker, D F, and Chance, P F. 1994. "Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy". United States.
@article{osti_6975546,
title = {Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy},
author = {Fain, P R and Barker, D F and Chance, P F},
abstractNote = {Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.},
doi = {},
url = {https://www.osti.gov/biblio/6975546}, journal = {American Journal of Human Genetics; (United States)},
issn = {0002-9297},
number = ,
volume = 54:2,
place = {United States},
year = {Tue Feb 01 00:00:00 EST 1994},
month = {Tue Feb 01 00:00:00 EST 1994}
}