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Title: Quality control and technical outcome of ISO-DALT two-dimensional electrophoresis in a clinical laboratory setting

Journal Article · · Clin. Chem. (Winston-Salem, N.C.); (United States)
OSTI ID:6935589

In this paper, they present initial quality-control evaluations for a prototype clinical laboratory, recommendations for clinical and technical data record-keeping, and laboratory protocols designed to minimize operator-dependent analytical error in a multi-user environment. These evaluations and recommendations are based on qualitative and semiquantitative two-dimensional electrophoresis studies of the College of American Pathologists' Reference Preparation for Serum Proteins (RPSP). They include the schematic map of RPSP and manually derived estimates of analytical precision for within-run and run-to-run performance with the standard 18 x 18 cm ISO-DALT system.

Research Organization:
Argonne National Lab, IL
DOE Contract Number:
W-31-109-ENG-38
OSTI ID:
6935589
Journal Information:
Clin. Chem. (Winston-Salem, N.C.); (United States), Vol. 30:12
Country of Publication:
United States
Language:
English