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Title: Abnormal cardiovascular responses induced by localized high power microwave exposure

Abstract

A hypothesis of microwave-induced circulatory under perfusion was tested in ketamine anesthetized rats whose heart rate, mean arterial pressure, pulse pressure, respiration rate, and body temperatures were monitored continuously. Fifty-eight ventral head and neck exposures in a waveguide consisted of sham-exposure and exposure to continuous wave (CW) and pulsed 1.25 GHz microwaves for 5 min. The 0.5 Hz and 16 Hz pulsemodulated microwaves were delivered at 400 kW peak power. The CW microwaves were 2 and 6.4 W. The average specific absorption rate was 4.75 W/kg per watt transmitted in the brain and 17.15 W/kg per watt transmitted in the neck. Respiration rate and mean arterial pressure were not altered. Changes in heart rate and pulse pressure were observed in rats exposed to higher power but not to the lower average power microwaves. Depression of pulse pressure, an indication of a decrease in stroke volume, and increased or decreased heart rate were noted in presence of whole-body hyperthermia. The cardiac output of those animals exposed to higher average power microwaves was considered to be below normal as hypothesized. Decreased cardiac output and normal mean arterial pressure resulted in an increase in the total peripheral resistance which was contrary to themore » anticipated thermal response of animals.« less

Authors:
; ; ;  [1];  [2]
  1. (ERC BioServices Corporation, Gaithersburg, MD (United States))
  2. (Walter Reed Army Institute of Research, Washington, DC (United States))
Publication Date:
OSTI Identifier:
6912990
Alternate Identifier(s):
OSTI ID: 6912990
Resource Type:
Journal Article
Resource Relation:
Journal Name: IEEE Transactions on Bio-Medical Engineering (Institute of Electrical and Electronics Engineers); (United States); Journal Volume: 39:5
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; HEART; SENSITIVITY; MICROWAVE RADIATION; BIOLOGICAL EFFECTS; BLOOD PRESSURE; HYPERTHERMIA; BODY; BODY TEMPERATURE; CARDIOVASCULAR SYSTEM; ELECTROMAGNETIC RADIATION; ORGANS; RADIATIONS 560400* -- Other Environmental Pollutant Effects

Citation Formats

Lu, S.-T, Brown, D.O., Johnson, C.E., Mathur, S.P., and Elson, E.C.. Abnormal cardiovascular responses induced by localized high power microwave exposure. United States: N. p., 1992. Web. doi:10.1109/10.135542.
Lu, S.-T, Brown, D.O., Johnson, C.E., Mathur, S.P., & Elson, E.C.. Abnormal cardiovascular responses induced by localized high power microwave exposure. United States. doi:10.1109/10.135542.
Lu, S.-T, Brown, D.O., Johnson, C.E., Mathur, S.P., and Elson, E.C.. Fri . "Abnormal cardiovascular responses induced by localized high power microwave exposure". United States. doi:10.1109/10.135542.
@article{osti_6912990,
title = {Abnormal cardiovascular responses induced by localized high power microwave exposure},
author = {Lu, S.-T and Brown, D.O. and Johnson, C.E. and Mathur, S.P. and Elson, E.C.},
abstractNote = {A hypothesis of microwave-induced circulatory under perfusion was tested in ketamine anesthetized rats whose heart rate, mean arterial pressure, pulse pressure, respiration rate, and body temperatures were monitored continuously. Fifty-eight ventral head and neck exposures in a waveguide consisted of sham-exposure and exposure to continuous wave (CW) and pulsed 1.25 GHz microwaves for 5 min. The 0.5 Hz and 16 Hz pulsemodulated microwaves were delivered at 400 kW peak power. The CW microwaves were 2 and 6.4 W. The average specific absorption rate was 4.75 W/kg per watt transmitted in the brain and 17.15 W/kg per watt transmitted in the neck. Respiration rate and mean arterial pressure were not altered. Changes in heart rate and pulse pressure were observed in rats exposed to higher power but not to the lower average power microwaves. Depression of pulse pressure, an indication of a decrease in stroke volume, and increased or decreased heart rate were noted in presence of whole-body hyperthermia. The cardiac output of those animals exposed to higher average power microwaves was considered to be below normal as hypothesized. Decreased cardiac output and normal mean arterial pressure resulted in an increase in the total peripheral resistance which was contrary to the anticipated thermal response of animals.},
doi = {10.1109/10.135542},
journal = {IEEE Transactions on Bio-Medical Engineering (Institute of Electrical and Electronics Engineers); (United States)},
number = ,
volume = 39:5,
place = {United States},
year = {Fri May 01 00:00:00 EDT 1992},
month = {Fri May 01 00:00:00 EDT 1992}
}