Stage T3 squamous cell carcinoma of the glottic larynx treated with surgery and/or radiation therapy

Journal Article · Thu Mar 01 00:00:00 EST 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90054-3· OSTI ID:6905043

Mendenhall, W M; Million, R R; Sharkey, D E; Cassisi, N J

This is a retrospective analysis of 68 patients with Stage T3 squamous cell carcinoma of the glottic larynx treated with surgery and/or irradiation from March 1965 to April 1981 at the University of Florida. Follow-up ranged from 2 to 17.5 years. Initial local-regional control of disease above the clavicles (i.e., prior to salvage attempts) by treatment technique for patients a risk for greater than or equal to 2 years was 11/19 (58%) with irradiation alone, 5/7 (71%) with preoperative irradiation and surgery, 8/9 (89%) with surgery and postoperative irradiation, and 18/23 (78%) with surgery alone. Initial control of disease at the primary site was accomplished in 11/18 (61%) treated with radiation therapy alone, and ultimate control of the primary was obtained in 15/18 (83%) after surgical salvage. Analysis of complications and survival is included, and treatment recommendations are discussed.

• Research Organization: Univ. of Florida Coll. of Medicine, Gainesville
• OSTI ID: 6905043
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:3
• Country of Publication: United States
• Language: English

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