Synthesis of oxazolines and oxazines

Patent · Tue Jan 17 00:00:00 EST 1995

OSTI ID:6879411

Benicewicz, B C; Mitchell, M A

A process is described for preparing an oxazoline or oxazine compound of the formula shown in the patent wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C[sub 1--10] alkyl, C[sub 1--10] fluoroalkyl, aryl and substituted-aryl, and n is 2 or 3 comprising ring-closing a compound of the formula also shown in the patent wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C[sub 1--10] alkyl, C[sub 1--10] fluoroalkyl, aryl, and substituted aryl, n is 2 or 3, and Y is a bromine or chlorine atom in the presence of a basic reagent consisting essentially of a fluoride salt supported on an inorganic solid substrate is disclosed together with the compounds, 5-bromomethyl-2-phenyl-1,3-oxazoline, 5-methylene-2-phenyl-1,3oxazine and 4,4-dimethyl-2-vinyl-1,3-oxazoline.

• Assignee: Dept. of Energy, Washington, DC (United States)
• Patent Number(s): US 5382665; A
• Application Number: PPN: US 8-032935
• OSTI ID: 6879411
• Resource Relation: Patent File Date: 17 Mar 1993
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ORGANIC NITROGEN COMPOUNDS
CHEMICAL PREPARATION
ORGANIC SULFUR COMPOUNDS
BROMIDES
CHLORIDES
FLUORIDES
MOLECULAR STRUCTURE
BROMINE COMPOUNDS
CHLORINE COMPOUNDS
FLUORINE COMPOUNDS
HALIDES
HALOGEN COMPOUNDS
ORGANIC COMPOUNDS
SYNTHESIS
400201* - Chemical & Physicochemical Properties