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Title: Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography

Abstract

Although used extensively, there is little published information on the prognostic ability of exercise /sup 201/Tl scintigraphy. Accordingly, 1 yr after testing we contacted 819 patients without previous MI or CABG seen in our laboratory during a 2-yr period. Events were defined as death from a cardiovascular cause, nonfatal MI, or worsening clinical state requiring CABG. The event rate was 3.9 events per 100 patients per year. There was univariate prognostic information when comparing the highest and lowest categories as risk ratios for chest pain characteristics (2.7), sex (2.3), exercise duration (3.1), ST slope (2.5), and thallium pattern (11.6), intensity of perfusion defect (17.2), and number of abnormal regions (8.7). However, the strongest predictors were also the least common. Prognostic ability was improved by combining the results categorically, as the number of abnormal tests (13.9). The highest risk ratio, 20.5:1, was obtained by combining results through discriminant function analysis. We conclude that exercise thallium scintigraphy provides prognostic information, although the most predictive patterns are uncommon. Combining the results of multiple test results improves the prognostic ability.

Authors:
; ; ;
Publication Date:
Research Org.:
Cedars-Sinai Medical Center, Los Angeles CA
OSTI Identifier:
6845234
Alternate Identifier(s):
OSTI ID: 6845234
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 12
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HEART; SCINTISCANNING; MYOCARDIAL INFARCTION; DIAGNOSIS; DEATH; ELECTROCARDIOGRAMS; EXERCISE; PATIENTS; THALLIUM 201; BETA DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIAGRAMS; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; HEAVY NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; THALLIUM ISOTOPES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics

Citation Formats

Staniloff, H.M., Forrester, J.S., Berman, D.S., and Swan, H.J. Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography. United States: N. p., 1986. Web.
Staniloff, H.M., Forrester, J.S., Berman, D.S., & Swan, H.J. Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography. United States.
Staniloff, H.M., Forrester, J.S., Berman, D.S., and Swan, H.J. Mon . "Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography". United States.
@article{osti_6845234,
title = {Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography},
author = {Staniloff, H.M. and Forrester, J.S. and Berman, D.S. and Swan, H.J.},
abstractNote = {Although used extensively, there is little published information on the prognostic ability of exercise /sup 201/Tl scintigraphy. Accordingly, 1 yr after testing we contacted 819 patients without previous MI or CABG seen in our laboratory during a 2-yr period. Events were defined as death from a cardiovascular cause, nonfatal MI, or worsening clinical state requiring CABG. The event rate was 3.9 events per 100 patients per year. There was univariate prognostic information when comparing the highest and lowest categories as risk ratios for chest pain characteristics (2.7), sex (2.3), exercise duration (3.1), ST slope (2.5), and thallium pattern (11.6), intensity of perfusion defect (17.2), and number of abnormal regions (8.7). However, the strongest predictors were also the least common. Prognostic ability was improved by combining the results categorically, as the number of abnormal tests (13.9). The highest risk ratio, 20.5:1, was obtained by combining results through discriminant function analysis. We conclude that exercise thallium scintigraphy provides prognostic information, although the most predictive patterns are uncommon. Combining the results of multiple test results improves the prognostic ability.},
doi = {},
journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 12,
place = {United States},
year = {1986},
month = {12}
}