Biochemical study of prolactin binding sites in Xenopus laevis brain and choroid plexus

Journal Article · Thu Mar 01 00:00:00 EST 1990 · Journal of Experimental Zoology; (USA)

DOI:https://doi.org/10.1002/jez.1402530310· OSTI ID:6828532

Muccioli, G; Guardabassi, A; Pattono, P ^[1]

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1. Univ. of Turin (Italy)

The occurrence of prolactin binding sites in some brain structures (telencephalon, ventral hypothalamus, myelencephalon, hypophysis, and choroid plexus) from Xenopus laevis (anuran amphibian) was studied by the in vitro biochemical technique. The higher binding values were obtained at the level of the choroid plexus and above all of the hypothalamus. On the bases of hormonal specificity and high affinity, these binding sites are very similar to those of prolactin receptors of classical target tissues as well as of those described by us in other structures from Xenopus. To our knowledge, the present results provide the first demonstration of the occurrence of prolactin specific binding sites in Xenopus laevis choroid plexus cells.

• OSTI ID: 6828532
• Journal Information: Journal of Experimental Zoology; (USA), Vol. 253:3; ISSN 0022-104X
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
BRAIN
BIOCHEMISTRY
LTH
RECEPTORS
TISSUE DISTRIBUTION
CELL MEMBRANES
FROGS
IODINE ISOTOPES
TRACER TECHNIQUES
AMPHIBIANS
ANIMALS
AQUATIC ORGANISMS
BODY
CELL CONSTITUENTS
CENTRAL NERVOUS SYSTEM
CHEMISTRY
DISTRIBUTION
GONADOTROPINS
HORMONES
ISOTOPE APPLICATIONS
ISOTOPES
MEMBRANE PROTEINS
MEMBRANES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PROTEINS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques