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Title: Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy

Abstract

A group of 26 patients with operable carcinoma of the breast received postoperative radiotherapy plus adjuvant chemotherapy. Acute skin reactions were studied by clinical observation. There was a statistically significant difference (P less than .01) in the acute skin reactions in the chest wall area in those who received chemotherapy (81%) compared to the controls who received only radiotherapy (33%). Acute skin reactions began at the completion of postoperative radiotherapy and reached maximum severity 1 to 2 weeks later. They usually subsided after 4 to 6 weeks. No skin reactions were observed in the parasternal, supraclavicular fossa, or axillary regions. On the basis of these findings, postoperative radiotherapy combined with adjuvant chemotherapy is probably beneficial.

Authors:
; ;
Publication Date:
Research Org.:
Orebro Regional Hospital, Sweden
OSTI Identifier:
6801307
Resource Type:
Journal Article
Journal Name:
Am. J. Roentgenol.; (United States)
Additional Journal Information:
Journal Volume: 130:1
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; PATIENTS; RADIOTHERAPY; SKIN; RADIATION EFFECTS; CARCINOMAS; CHEMOTHERAPY; CHEST; DAMAGE; ETIOLOGY; MAMMARY GLANDS; RESPONSE MODIFYING FACTORS; BODY; BODY AREAS; DISEASES; GLANDS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY; 560151* - Radiation Effects on Animals- Man

Citation Formats

Hahn, P, Hallberg, O, and Vikterloef, K J. Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy. United States: N. p., 1978. Web. doi:10.2214/ajr.130.1.137.
Hahn, P, Hallberg, O, & Vikterloef, K J. Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy. United States. https://doi.org/10.2214/ajr.130.1.137
Hahn, P, Hallberg, O, and Vikterloef, K J. 1978. "Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy". United States. https://doi.org/10.2214/ajr.130.1.137.
@article{osti_6801307,
title = {Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy},
author = {Hahn, P and Hallberg, O and Vikterloef, K J},
abstractNote = {A group of 26 patients with operable carcinoma of the breast received postoperative radiotherapy plus adjuvant chemotherapy. Acute skin reactions were studied by clinical observation. There was a statistically significant difference (P less than .01) in the acute skin reactions in the chest wall area in those who received chemotherapy (81%) compared to the controls who received only radiotherapy (33%). Acute skin reactions began at the completion of postoperative radiotherapy and reached maximum severity 1 to 2 weeks later. They usually subsided after 4 to 6 weeks. No skin reactions were observed in the parasternal, supraclavicular fossa, or axillary regions. On the basis of these findings, postoperative radiotherapy combined with adjuvant chemotherapy is probably beneficial.},
doi = {10.2214/ajr.130.1.137},
url = {https://www.osti.gov/biblio/6801307}, journal = {Am. J. Roentgenol.; (United States)},
number = ,
volume = 130:1,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1978},
month = {Sun Jan 01 00:00:00 EST 1978}
}