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Title: Activated recombinant adenovirus proteinases

Abstract

This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.

Inventors:
;
Publication Date:
Sponsoring Org.:
USDOE, Washington, DC (United States); National Insts. of Health, Bethesda, MD (United States)
OSTI Identifier:
678582
Patent Number(s):
US 5,935,840/A/
Application Number:
PAN: 8-435,998; CNN: Grant U01 A126049
Assignee:
Associated Universities, Inc., Washington, DC (United States) PTO; SCA: 550200; PA: EDB-99:086046; SN: 99002124524
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 10 Aug 1999
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; PURIFICATION; PEPTIDE HYDROLASES; ADENOVIRUS; ANTIBODIES; IMMUNE REACTIONS

Citation Formats

Anderson, C.W., and Mangel, W.F. Activated recombinant adenovirus proteinases. United States: N. p., 1999. Web.
Anderson, C.W., & Mangel, W.F. Activated recombinant adenovirus proteinases. United States.
Anderson, C.W., and Mangel, W.F. Tue . "Activated recombinant adenovirus proteinases". United States.
@article{osti_678582,
title = {Activated recombinant adenovirus proteinases},
author = {Anderson, C.W. and Mangel, W.F.},
abstractNote = {This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {8}
}