Metabolism of americium-241 in dairy animals. [Cows and goats]
Groups of lactating cows and goats were used to examine americium-241 metabolism in dairy animals. Following either single oral or intravenous nuclide doses, samples of milk, urine, blood, and feces were taken over a 168-hr collection period and the americium concentrations were determined by gamma counting. Gastrointestinal uptake of americium by both cows and goats was estimated to be 0.014% of the respective oral doses. The cumulative percentage of oral dose transported to milk and urine was 4.4 x 10/sup -4/ and 1.1 x 10/sup -3/ respectively for cows and 4.4 x 10/sup -3/ and 1.2 x 10/sup -3/ respectively for goats. The relatively high americium concentrations noted in caprine milk following the oral doses are discussed. Plasma concentrations of americium decreased rapidly following all intravenous injections. The average percentage of injected americium transferred to milk, urine, and feces was 3, 6, and 2% respectively for cows and 2, 4, and 2% respectively for goats. In both intravenously dosed groups, approximately 30% of all americium released from the body was found in the urine during the first 24 hrs after injection. All animals were sacrificed 8 to 9 days after dosing. Bovine bone retained the greatest fraction of the administered dose followed by the liver. However, liver retained the greatest amount of americium in the goats following both oral and intravenous doses. Comparisons are presented between americium-241 and plutonium-238 transport in dairy cows.
- Research Organization:
- Environmental Protection Agency, Las Vegas, NV (USA). Environmental Monitoring and Support Lab.
- DOE Contract Number:
- EY-76-A-0539
- OSTI ID:
- 6776026
- Report Number(s):
- EMSL-LV-0539-22; TRN: 79-003351
- Country of Publication:
- United States
- Language:
- English
Similar Records
I$sup 131$ CONCENTRATIONS IN BLOOD, MILK, URINE AND FECES OF DAIRY COWS FOLLOWING A SINGLE DOSE OF RADIO-IODINE
Dietary lead and metabolism of /sup 210/Pb and stable Pb in sheep
Related Subjects
AMERICIUM 241
INTESTINAL ABSORPTION
METABOLISM
TISSUE DISTRIBUTION
COWS
RADIONUCLIDE KINETICS
GOATS
COMPARATIVE EVALUATIONS
FECES
INTRAVENOUS INJECTION
LACTATION
LIVER
MILK
ORAL ADMINISTRATION
PLUTONIUM 238
SINGLE INTAKE
SKELETON
URINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
AMERICIUM ISOTOPES
ANIMALS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY
BODY FLUIDS
CATTLE
DIGESTIVE SYSTEM
DISTRIBUTION
DOMESTIC ANIMALS
EVEN-EVEN NUCLEI
FOOD
GLANDS
HEAVY NUCLEI
INJECTION
INTAKE
ISOTOPES
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PLUTONIUM ISOTOPES
RADIOISOTOPES
RUMINANTS
UPTAKE
VERTEBRATES
WASTES
YEARS LIVING RADIOISOTOPES
560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)