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Title: Scintigraphic appearances of osteoid osteoma

Abstract

A series of 42 osteoid osteomas is reviewed, and the scintigraphic appearances are described. In all cases, a marked, well-localized area of increased activity was demonstrated at the tumor site in both the blood-pool and standard two-hour images. The blood-pool images were performed after the injection of technetium-99m methylene diphosphate which showed a small hyperemic lesion in all cases of osteoid osteoma, thus distinguishing this tumor from other lesions which may show uptake of radionuclide activity after two hours.

Authors:
;
Publication Date:
Research Org.:
Hospital for Sick Children, Toronto, Ontario
OSTI Identifier:
6757380
Resource Type:
Conference
Resource Relation:
Journal Name: Radiology; (United States); Journal Volume: 137:1; Conference: 66. scientific assembly and annual meeting of the Radiological Society of North America, Dallas, TX, USA, 16 Nov 1980
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD FLOW; RADIONUCLIDE KINETICS; SCINTISCANNING; NEOPLASMS; DIAGNOSIS; SKELETON; TECHNETIUM 99; ISOMERIC NUCLEI; LABELLED COMPOUNDS; PHOSPHATES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; OXYGEN COMPOUNDS; PHOSPHORUS COMPOUNDS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES 560171* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987); 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics

Citation Formats

Smith, F.W., and Gilday, D.L. Scintigraphic appearances of osteoid osteoma. United States: N. p., 1980. Web.
Smith, F.W., & Gilday, D.L. Scintigraphic appearances of osteoid osteoma. United States.
Smith, F.W., and Gilday, D.L. 1980. "Scintigraphic appearances of osteoid osteoma". United States. doi:.
@article{osti_6757380,
title = {Scintigraphic appearances of osteoid osteoma},
author = {Smith, F.W. and Gilday, D.L.},
abstractNote = {A series of 42 osteoid osteomas is reviewed, and the scintigraphic appearances are described. In all cases, a marked, well-localized area of increased activity was demonstrated at the tumor site in both the blood-pool and standard two-hour images. The blood-pool images were performed after the injection of technetium-99m methylene diphosphate which showed a small hyperemic lesion in all cases of osteoid osteoma, thus distinguishing this tumor from other lesions which may show uptake of radionuclide activity after two hours.},
doi = {},
journal = {Radiology; (United States)},
number = ,
volume = 137:1,
place = {United States},
year = 1980,
month =
}

Conference:
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  • Bone scanning with /sup 99m/Tc-diphosphonate disclosed a solitary focus of intense activity in a cervical vertebra of a 17-year-old youth with persistent unexplained neck pain. Surgery subsequently demonstrated a well-circumscribed osteoid osteoma. This experience is further evidence of the efficacy of radionuclide skeletal scintigraphy in the evaluation of benign bone disease.
  • The double-density sign, seen on radionuclide bone scans, is described for diagnosing osteoid osteomas and for localizing the nidus. Its use in differentiating the nidus of an osteoid osteoma from osteomyelitis is also described. The utility of computed tomography in localization of the nidus is also illustrated. The double-density sign was helpful in diagnosing seven cases of surgically confirmed osteoid osteoma.
  • Osteoid osteoma is a benign bone tumor which is most often seen in young males. Several imaging techniques have been used for the detection of osteoid osteoma lesions. Conventional x-ray was found to detect only two-thirds of lesions. Computerized tomography has been used to determine the extent of the osteoid osteoma's progress, particularly the soft tissue involvement. In this study, the radionuclide three-phase bone scan was positive in all six patients with surgically proven osteoid osteoma. In addition, nuclear medicine scans of bone specimens may be used to predict whether all of the tumor has been removed. Incomplete excision willmore » likely result in recurrence. Since /sup 99m/Tc-MDP (methylene diphosphonate) is blood borne, it reflects blood flow to the tumor site. It also adsorbs onto the hydroxyapatite crystal. Its concentration is proportional to osteoblastic activity. A study was undertaken to evaluate the use of the three-phase bone scan in patient's referred with possible osteoid osteoma. In addition, scans of bone samples were used during the surgical procedures to evaluate complete tumor renewal.« less
  • We report two cases of osteoid osteoma of the acetabulum associated with severe chronic synovitis. The diagnosis is difficult and usually delayed because the acetabulum is a rare site for this tumor and clinical signs are nonspecific. Computed tomography (CT) scanning is the best diagnostic technique. An intraarticular surgical approach allows complete resection, but one case required spongy bone grafts. Postoperative results are excellent.