Hydrocarbons disposition, lipid content, and fatty acid composition in trout after long-term dietary exposure to n-alkanes

Journal Article · Thu Dec 01 00:00:00 EST 1983 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(83)90121-4· OSTI ID:6748123

Cravedi, J P; Tulliez, J E

Uptake, distribution, and storage of n-alkanes was studied in rainbow trout receiving a diet containing 1% normal paraffins in the C/sub 13/-C/sub 22/ range. After 3 months, the concentration of hydrocarbons deposited in the whole body reached a steady equilibrium value in the range 700-900 ppm. The most pronounced deposition occurred in the adipose tissue. The n-alkane pattern in the whole body exhibited a profile different from that of the alkane mixture ingested. The alkanes around C/sub 20/ were not retained to any great extent, but as the chain length decreased, the relative amount stored increased. In the liver a marked predominance of even-carbon chain length was observed while in whole fish and in other organs such a phenomenon did not occur. After 5 months, total lipids in the carcass were significantly lower in the test group than in the control group. At the end of the accumulation period, a significant enhancement in the proportion of odd- and even-chain saturated fatty acids from C/sub 14:0/ to C/sub 18:0/ was noted in carcasses of hydrocarbon-fed fish. Myristic, pentadecanoic, and heptadecanoic acids were also significantly more abundant in the liver and adipose tissue of contaminated fish. This increase is attributed to the terminal oxidation of the predominant n-alkanes in the diet into the corresponding fatty acids. During the depuration period, one-half of the trout in each group were fed a hydrocarbon-free diet, while the others were starved. After 2 months, both starved and fed trout had lost approximately 50% of the amount of total n-alkanes stored. The n-alkanes longer than C/sub 16/ were well retained, while short-chain alkane concentration decreased rapidly. 41 references.

• Research Organization: Laboratoire de Recherches sur les Additifs Alimentaires, Toulouse, France
• OSTI ID: 6748123
• Journal Information: Environ. Res.; (United States), Vol. 32:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
BIOLOGICAL EFFECTS
CHRONIC INTAKE
TISSUE DISTRIBUTION
TROUT
CONTAMINATION
ADIPOSE TISSUE
BIOLOGICAL ACCUMULATION
CARBOXYLIC ACIDS
CONCENTRATION RATIO
INGESTION
LIVER
ANIMAL TISSUES
ANIMALS
AQUATIC ORGANISMS
BODY
CONNECTIVE TISSUE
DIGESTIVE SYSTEM
DISTRIBUTION
FISHES
GLANDS
HYDROCARBONS
INTAKE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
TISSUES
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)