The effect of short-term corticosteroid treatment on the CT appearance of experimental brain abscesses. [Dogs]

Journal Article · Fri Oct 01 00:00:00 EDT 1982 · Radiology; (United States)

OSTI ID:6710375

Enzmann, D R; Britt, R H; Placone, Jr, R C; Obana, W; Lyons, B; Yeager, A S

The effect of short-term corticosteroid treatment on contrast enhancement was investigated in an experimental brain abscess model. The degree of enhancement was reduced in the cerebritis stage, unaffected in the capsule stage, and intermediate in the transitional stage. The area and pattern of enhancement were also altered in the cerebritis stage. Although the magnitude of the entire cerebritis time-density curve (extended for 60 minutes) was decreased by the steroids, its configuration was unchanged. Prior to steroid administration, the 10- and 60-minute components of the curve discriminated between cerebritis and capsule stages, with the latter exhibiting a far lower 60-minute value. Implications for treatment of brain abscesses are discussed.

• Research Organization: Stanford Univ., CA
• OSTI ID: 6710375
• Journal Information: Radiology; (United States), Vol. 145:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ABSCESSES
DIAGNOSIS
BRAIN
COMPUTERIZED TOMOGRAPHY
DYNAMIC FUNCTION STUDIES
CORTICOSTEROIDS
BIOLOGICAL EFFECTS
DOGS
ADRENAL HORMONES
ANIMALS
BODY
CENTRAL NERVOUS SYSTEM
DIAGNOSTIC TECHNIQUES
HORMONES
HYDROXY COMPOUNDS
KETONES
MAMMALS
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PREGNANES
STEROID HORMONES
STEROIDS
TOMOGRAPHY
VERTEBRATES
550602* - Medicine- External Radiation in Diagnostics- (1980-)