Preparation and use of a /sup 195m/Au-containing liquid
A process is described for performing a radiodiagnositc examination in a living being comprising administering to the living being a non-toxic, pharmaceutically acceptable /sup 195m/Au-containing liquid which is produced by (a) adsorbing /sup 195m/Hg on a chemically and radiolytically stable adsorption agent comprising a mercury ion binding material having a significantly higher affinity to mercury ions than for gold ions, and (b) eluting the daughter /sup 195m/Au radioisotope with an eluant which selectively converts /sup 195m/Au ions to an elutable form in the presence of the adsorbed parent /sup 195m/Hg radioisotope, and which is non-toxic and pharmaceutically acceptable, and monitoring the radioactivity emitted from the living being.
- Assignee:
- Mallinckrodt Diagnostica
- Patent Number(s):
- US 4643891
- Application Number:
- TRN: 87-015094
- OSTI ID:
- 6702945
- Resource Relation:
- Patent File Date: Filed date 14 Oct 1983
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
GOLD 195
DIAGNOSTIC USES
RADIOISOTOPE GENERATORS
DESIGN
ADSORPTION
AFFINITY
BINDERS
DAUGHTER PRODUCTS
HUMAN POPULATIONS
MERCURY 195
RADIOPHARMACEUTICALS
BETA DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GOLD ISOTOPES
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MERCURY ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
POPULATIONS
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
SORPTION
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400202 - Isotope Effects
Isotope Exchange
& Isotope Separation