Does endothelin mobilize calcium from intracellular store sites in rat aortic vascular smooth muscle cells in primary culture

Journal Article · Fri Oct 14 00:00:00 EDT 1988 · Biochem. Biophys. Res. Commun.; (United States)

DOI:https://doi.org/10.1016/S0006-291X(88)80841-6· OSTI ID:6603181

Miasiro, N; Yamamoto, H; Kanaide, H; Nakamura, M

In the presence of endothelin, there was a rapid increase in the /sup 45/Ca++ efflux from primary cultured rat vascular smooth muscle cells, both in physiological salt solution and in calcium free medium containing 2 mM EGTA. The /sup 45/Ca++ influx was not affected. The endothelin-induced, transient increase in cytosolic calcium concentration is probably mainly due to release of calcium from the intracellular store in vascular smooth muscle cells.

• Research Organization: Kyushu Univ., Fukuoka (Japan)
• OSTI ID: 6603181
• Journal Information: Biochem. Biophys. Res. Commun.; (United States), Vol. 156:1
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
PEPTIDES
BIOCHEMICAL REACTION KINETICS
AORTA
CALCIUM
CALCIUM 45
CELL CULTURES
MEMBRANE TRANSPORT
MUSCLES
RATS
TRACER TECHNIQUES
ALKALINE EARTH ISOTOPES
ALKALINE EARTH METALS
ANIMALS
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CALCIUM ISOTOPES
CARDIOVASCULAR SYSTEM
DAYS LIVING RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
KINETICS
MAMMALS
METALS
NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOISOTOPES
REACTION KINETICS
RODENTS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques