Relationship between external and internal parameters of exposure to manganese in workers from a manganese oxide and salt producing plant

Journal Article · Thu Jan 01 00:00:00 EST 1987 · Am. J. Ind. Med.; (United States)

DOI:https://doi.org/10.1002/ajim.4700110307· OSTI ID:6496506

Roels, H; Lauwerys, R; Genet, P; Sarhan, M J; de Fays, M; Hanotiau, I; Buchet, J P

In a plant producing manganese (Mn) oxides and salts, 11 different workplaces were identified. The current exposure to airborne Mn (total dust, personal sampling, n = 80) varied from 0.07 to 8.61 mg/m3. The geometric mean and median values amounted approximately to 1 mg/m3 and the 95th percentile was 3.30 mg/m3. The concentration of Mn in blood (Mn-B) in a group of 141 Mn-exposed male workers ranged from 0.10-3.59 micrograms/100 ml compared to 0.04-1.31 micrograms/100 ml in a group of 104 control subjects. The ranges of the concentrations of Mn in urine (Mn-U) were 0.06-140.6 and 0.01-5.04 micrograms/g creatinine for the exposed and control groups, respectively. The average level of Mn-B in the Mn group was more than twice as high as in the control group (arithmetic mean, 1.36 vs 0.57 microgram/100 ml) and that of Mn-U was ten times higher in the Mn group (geometric mean, 1.56 vs 0.15 microgram/g creatinine). The Mn-B level did not change significantly after 8 h of Mn exposure, whereas the Mn-U level dropped rapidly when exposure ceased (half-life less than 30 h). On an individual basis, neither Mn-B nor Mn-U correlated with the current levels of Mn-air or duration of Mn exposure. There was also no relationship between Mn-B and Mn-U. On a group basis, there was no correlation between the mean Mn-B levels and the current levels of Mn-air at each workplace.

• Research Organization: Univ. of Louvain, Brussels, Belgium
• OSTI ID: 6496506
• Journal Information: Am. J. Ind. Med.; (United States), Vol. 3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
54 ENVIRONMENTAL SCIENCES
MANGANESE
ECOLOGICAL CONCENTRATION
UPTAKE
BLOOD
INDOOR AIR POLLUTION
OCCUPATIONAL EXPOSURE
PERSONNEL
URINE
AIR POLLUTION
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
ELEMENTS
MATERIALS
METALS
POLLUTION
TRANSITION ELEMENTS
WASTES
560300* - Chemicals Metabolism & Toxicology
500200 - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)