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Title: Fibrosarcoma complicating irradiated pituitary adenoma

Journal Article · · Surg. Neurol. (Tryon, N.C.); (United States)

Eight years after radiation therapy (5000 rads of 60Co) for a pituitary adenoma, a patient developed a sellar fibrosarcoma. The tumor had an aggressive growth pattern: it infiltrated the optic nerve, sphenoidal air sinus, hypothalamus, and both cavernous sinuses, where compression of the left internal carotid artery resulted in a massive hemispheric infarction. Surgery was ineffective in arresting rapid growth of the lesion; death occurring 5 months after onset of symptoms.

Research Organization:
Department of Pathology, Neuropathology, University Hospital, University of Western Ontario, London, Canada
OSTI ID:
6476773
Journal Information:
Surg. Neurol. (Tryon, N.C.); (United States), Vol. 22:3
Country of Publication:
United States
Language:
English